首页> 中文期刊> 《中国神经再生研究(英文版)》 >Cognitive malingering assessed using event-related potential P300 evoked by the old-new task in the oddball paradigm

Cognitive malingering assessed using event-related potential P300 evoked by the old-new task in the oddball paradigm

         

摘要

The P300,an endogenous subcomponent of the event-related potential,is thought to reflect cognitive processes.The event-related potential evoked by the old-new memory recognition task in the oddball paradigm is suitable for examining the neural processes involved in malingered neurocognitive deficits.Forty-four undergraduates were randomly assigned to a simulated malingering group and a truth-telling group.Another 22 patients with head injuries were enrolled as a control group.All participants completed the old-new memory recognition task in the oddball paradigm.The mean P300 amplitude of the simulated malingering group was significantly reduced compared with the truth-telling group (P<0.01),but was increased compared with the control group (P<0.01).These results revealed that the P300,evoked by the old-new memory recognition task of the oddball paradigm,may be a helpful indicator for determining cognitive malingering.

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