Objectives To assess effects of Losartan on echocatrdiographic left heart morphology,function in patientswith congestive heart failure(CHF).Methods 36 patients with CHF treated with oral Losartan(50mg daily)for 2～4 weeks on base of usually treated,examined by eohocaridiography.Results The results showed that Left ventricular diameter(LVD) were significantly changed(P＜0.01),Letf heart function parameters were also increased significantly(P＜0.01).Conclusions These results showed that Losartan in the treatment of patient with CHF is benefical on acute hamemodynamic and decreased Left ventricult diameter.%目的 观察氯沙坦治疗充血性心力衰竭患者左心形态及功能的变化。方法 对36例充血性心力衰竭患者在常规治疗的基础上口服氯沙坦50mg/d 2～4周，治疗前后进行M型、二维、多普勒超声心动图检测。结果 治疗前后患者左室内径(LVD)恢复明显(P＜0.01)，左心功能指标也明显改善(P＜0.01)。结论 氯沙坦对充血性心力衰竭患者血流动力学异常有明显的改善作用，并能使左室扩大程度减轻。
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