The nuclear power plant ( NPP) pump building which is important to supply water for the es⁃sential service water system belongs to seismic category I structure� For safety evaluation, the 2D plane strain and 3D FEM model of non-uniform foundation of a pump building are created, and the static set⁃tlement calculation at the stages of construction and normal operation is carried out� Furthermore, on the basis of the essential concepts of harmonic response analysis, an improved numerical solution to the soil dynamic impedance of the 3D free field is presented in this paper, by utilizing visco⁃elastic soil dynamic model, which is especially fit for the numerical simulation of non⁃homogeneous soil region� The results of the static settlement and the dynamic impedance of the non⁃uniform foundation are both compared to those of fictitious uniform foundation� The conclusion may provide basis in the aspect of the pump building structure design.%核电机组的重要厂用水泵房作为核电厂重要的取水构筑物，属于抗震I类物项。为了评价某泵房不均匀地基的安全性，本文分别建立了不均匀地基的平面应变和三维有限元模型，对其进行了施工阶段与正常运行期间的非线性静力沉降计算。此外，本文从谐响应动力求解方法的基本概念出发，基于粘弹性人工边界场地模型，进行了三维自由场地的动阻抗计算，以上结果均与假想的均质地基结果进行对比分析，为下一步泵房结构的抗震计算分析提供了依据。
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