How crystal configuration affects the position detection accuracy in pixelated molecular SPECT imaging systems?

Hojjat Mahani; Gholamreza Raisali; Alireza Kamali-Asl; Mohammad Reza Ay

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How crystal configuration affects the position detection accuracy in pixelated molecular SPECT imaging systems?

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It is well known that inter-crystal scattering and penetration(ICS-P) are major spatial resolution limiting parameters in dedicated SPECT scanners with pixelated crystal.In this study,the effect of ICS-P on crystal identification in different crystal configurations was evaluated using GATE Monte Carlo simulation.A ^(99m)Tc pencil-beam toward central crystal element was utilized.Beam incident angle was assumed to vary from 0° to 45° in 5° steps.The effects of various crystal configurations such as pixel-size,pixel-gap,and crystal material were studied.The influence of photon energy on the crystal identification(CI) was also investigated.Position detection accuracy(PDA) was defined as a factor indicating performance of the crystal.Furthermore,a set of ^(99m)Tc point-source simulations was performed in order to calculate peak-to-valley(PVR) ratio for each configuration.The results show that the CsI(Na)manifests higher PDA than NaI(TI) and YAP(Ce).In addition,as the incident angle increases,the crystal becomes less accurate in positioning of the events.Beyond a crystal-dependent critical angle,the PDA monotonically reduces.The PDA reaches 0.44 for the CsI(Na) at 45° beam angle.The PDAs obtained by the point-source evaluation also behave the same as for the pencil-beam irradiations.In addition,the PVRs derived from flood images linearly correlate their corresponding PDAs.In conclusion,quantitative assessment of ICS-P is mandatory for scanner design and modeling the system matrix during iterative reconstruction algorithms for the purpose of resolution modeling in ultra-high-resolution SPECT.

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《核技术：英文版》 |2017年第4期|24-30|共7页
作者
Hojjat Mahani; Gholamreza Raisali; Alireza Kamali-Asl; Mohammad Reza Ay;
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作者单位

Radiation Application Research School;

Nuclear Science and Technology Research Institute;

Tehran;

Iran;

Research Center for Molecular and Cellular Imaging;

Tehran University of Medical Science;

Tehran;

Iran;

Radiation Medicine Department;

Shahid Beheshti University;

Tehran;

Iran;

Department of Medical Physics and Biomedical Engineering;

Tehran University of Medical Science;

Tehran;

Iran;

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原文格式 PDF
正文语种 chi
中图分类原子能技术;
关键词
Monte; Carlo; GATE; Molecular; SPECT; Position; detection; accuracy; Pixelated; crystal;

How crystal configuration affects the position detection accuracy in pixelated molecular SPECT imaging systems?

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