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Application of pharmacokinetics local model to evaluate renal function

机译:药代动力学局部模型在评估肾功能中的应用

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摘要

The pharmacokinetics local model was used to evaluate renal function.Some typical kinds of renal function cases, normal or disorder, were selected to be imaged with SPECT and those data measured were treated by the pharmacokinetics local model computer program (PLM).The results indicated that parameters, including peak value, peak time, inflexion time, half-excretion time, and kinetic equation played and importantrole in judging renal function.The fact confirms that local model isvery useful in evaluating renal function.
机译:使用药代动力学局部模型评估肾功能,选择一些典型类型的正常或异常肾功能病例进行SPECT成像,并通过药代动力学局部模型计算机程序(PLM)处理所测量的数据。该参数包括峰值,峰值时间,屈曲时间,半排泄时间和动力学方程,对判断肾功能起着重要作用。事实证明,局部模型对于评估肾功能非常有用。

著录项

  • 来源
    《核技术(英文版)》 |1999年第1期|28-30|共3页
  • 作者

  • 作者单位

    Jianyuan Hospital, State KeyLaboratory of Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063;

    Jianyuan Hospital, State KeyLaboratory of Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063;

    Jianyuan Hospital, State KeyLaboratory of Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063;

  • 收录信息 中国科学引文数据库(CSCD);
  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类 物理学;
  • 关键词

    Renal function; Pharmacokinetics; Localmodel; SPECT;

    机译:肾功能;药代动力学;局部模型;SPECT;
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