In order to understand the molecules mechanism of ion irradiation,which has been widelyused in many fields such as cancer therapy, uracil, one of the bases ofnucleic acid,waschosen in the low energy ion radiolysis research. The solid uracil films with mass thickness of0.314 mg/cm2 were irradiated by 200 keV H+ ions.The experimental results show that 200 keVH+ ions are effective in decomposition of uracil molecules. One of the decomposition products,5,6-dihydro-uracil, was separated by high performance liquid chromatograph (HPLC) anddetected using an UV-light detector. Its yield increases first but then decreases as the ion doseincreasing. In addition, the mechanism of uracil decomposition and 5,6-dihydro-uracilformation was also discussed.
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机译：为了了解离子辐照的分子机理，在低能离子辐解研究中选择了广泛用于癌症治疗，尿酸作为核酸基础之一的尿嘧啶。用200 keV H +离子辐照质量厚度为0.314 mg / cm2的固态尿嘧啶薄膜。实验结果表明，200 keVH +离子可有效分解尿嘧啶分子。通过高效液相色谱（HPLC）分离分解产物之一5,6-二氢尿嘧啶，并使用紫外光检测器进行检测。随着离子剂量的增加，其收率先增加，然后降低。此外，还讨论了尿嘧啶分解和5，6-二氢尿嘧啶形成的机理。
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