Objective To observe the effects of different interventions of syntony under 4 Hz on the markers in serum such as alkaline phosphatase (BALP),6-keto prostaglandin 1α (6-keto-PGF 1α) and malondialdehyde (MDA) in rabbits. Methods Sevety-five New Zealand white rabbits were randomly divided into five groups:control group,matched control group, Ⅰ model group, Ⅱ model group and Ⅲ model group,n=15 for each. The activity of BALP,6-keto-PGF 1α and MDA in serum were determined at the 2nd,4th and 6th week after treatment. Results Compared with the control group and Ⅲ model group,BALP,6-keto-PGF 1α and MDA in the matched control group, Ⅰ model group and Ⅱ model group ascended at the 4th and 6th week (P<0.05). Compared with matched control group,BALP and 6-keto-PGF 1α in the control group and Ⅲ model group were reduced since the 4th week,MDA were reduced since the 6th week (P<0.05). Conclusion The intervention of syntony has very important reference value for early prevention of low back pain caused by syntony.%目的：在4 Hz谐振频率下不同干预方式对兔抗谐振后观察血清代谢标志物特异性碱性磷酸酶（BALP）、6－酮前列腺素1α（6－keto－PGF 1α）的含量及丙二醛（MDA）含量的影响。方法75只新西兰兔随机均分为正常对照组、造模对照组及3个谐振干预实验组，每组15只，分别于实验的2、4、6周每组中随机抽取5只在清晨空腹下经耳缘静脉穿刺抽取5 ml静脉血，装于抗凝试管，测定血清中特异性碱性磷酸酶（BALP）、6－酮前列腺素1α（6－keto－PGF 1α）及丙二醛（MDA）含量并观察动态变化。结果与正常对照组和谐振干预3组比较，造模对照组、谐振干预1、2组BALP、6－keto－PGF 1α第4周开始升高，MDA含量从第6周开始升高且差异显著（P＜0．05）。与造模对照组相比，正常对照组、谐振干预3组BALP、6－keto－PGF 1α和MDA的含量在第4、6周降低且谐振干预1、2组与谐振干预3组同期相比差异显著（P＜0．05）。结论不同干预对谐振引起的下腰痛早期防治具有重要参考价值，尤以PEP加工成大小不同空心棉球组成表面凹凸不平的坐垫对于防治下腰痛发生具有重要意义。
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