Molecularly imprinted polymer（MIP）,a material which owns artificially-created binding sites coupled with several distinct advantages such as high chemical,mechanical and thermal stability,robust,easy preparation,low cost and reusable.MIP as mimic in pseudo-immunoassays have attracted considerable attention over the last few years.The advances in molecularly imprinted sorbent immunoassays（MIAs） are reviewed from radioligand immunoassays to non-radioligand immunoassays,and emphasize on the promotion which homogeneous immunoassay systems and new synthesis methods bring.It is shown that the perceived disadvantages of MIP can be ignored in MIAs.The existing problems and prospects of MIAs are also described.%分子印迹聚合物是一种含特异性识别位点的高分子材料,具有高稳定性、低成本、制备简单和可重复利用等特点,常被作为仿生抗体应用于免疫分析。本文综述了分子印迹免疫吸附分析（molecularlyimprinted sorbent immunoassays,MIAs）的研究进展,介绍了以不同标记物为探针的仿生免疫分析方法的发展,着重介绍了均相免疫分析系统与分子印迹聚合物的新型合成方法在MIAs中的应用。最后,本文指出分子印迹聚合物的一些缺点并没有阻碍其在免疫吸附分析中的应用,并对MIAs仍然存在的问题和发展前景进行了分析。
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