首页> 中文期刊> 《现代中药研究与实践》 >“九蒸九晒”传统炮制对何首乌主要化学成分的影响

“九蒸九晒”传统炮制对何首乌主要化学成分的影响

         

摘要

Objective To measure the content of the main components of Polygonum multiflorum after the nine-time repeat of the steaming and sun-drying traditional processing,and to provide theoretical basis for the ancient processing way ofPolygonum multiflorum.Methods To steam with black beans and measure the content of free anthraquinone and stilbene glucoside in Polygonum multiflorum according to the method in Chinese Pharmacopoeia (2015).Results The content of free anthraquinone increased from 0.130% to 0.174% after processing,but the content of some intermediates decreased.The content of stilbene glycoside decreased from 5.42% to 2.10% after processing.Conclusion The content of emodin and physcion in the process of Polygonum multiflorum rises first then decreases,later shows a slow growth.The overall trend is rising;the content of stilbene glycoside shows a gradual decline.%目的 对何首乌经九蒸九晒后其主要成分的含量进行分析,为何首乌古法炮制提供理论依据方法 采用传统的黑豆共蒸法进行九蒸九晒炮制,参照2015版《中国药典》方法测定炮制后何首乌中游离蒽醌及二苯乙烯苷的含量.结果 游离蒽醌含量从炮制前的0.130%上升至炮制后的0.174%,但某些炮制中间品的含量下降;二苯乙烯苷含量从炮制前的5.42%下降至炮制后的2.10%.结论 何首乌九蒸九晒过程中大黄素和大黄素甲醚呈现先上升后下降再缓上升,总体呈上升的趋势;二苯乙烯苷的含量呈明显的梯度下降.

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