目的：探讨2型糖尿病（DM）合并高尿酸血症（HUA）患者血压及血脂水平的关系。方法：纳入30例2型糖尿病患者非高尿酸血症患者作为A组，30例高尿酸血症非2型糖尿病患者为B组，30例2型糖尿病合并高尿酸血症患者为C组，另随机选取我院门诊健康查体者30例为正常对照组D组，所有研究对象均测量其血压和血脂水平并进行分析比较。结果：①与正常对照组相比，糖尿病非高尿酸血症组患者血压收缩压、舒张压、高胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）均升高，差异具有统计学意义（P＜0．05），高密度脂蛋白胆固醇（HDL-C）降低具有显著统计学差异（P＜0．05）。②高尿酸血症非2型糖尿病患者与对照组相比，血压收缩压、TC、TG、LDL-C升高，HDL-C降低，差异具有统计学意义（P＜0．05），舒张压升高无统计学意义（P＞0．05）。③2型糖尿病合并高尿酸血症患者与正常组患者相比血压收缩压、舒张压、TC、TG、LDL-C均明显升高，差异具有统计学意义（P＜0．05），HDL-C降低具有显著统计学差异（P＜0．05）。④2型糖尿病合并高尿酸血症患者与糖尿病非高尿酸血症组患者相比血压收缩压、TC、TG明显升高，差异具有统计学意义（P＜0．05）。⑤2型糖尿病合并高尿酸血症患者与高尿酸血症非2型糖尿病患者相比血压收缩压、TC、TG明显升高，差异具有统计学意义（P＜0．05）。结论：2型糖尿病合并高尿酸血症的患者血压收缩压、舒张压、TC、TG、LDL-C均明显升高，HDL-C降低。在临床工作中，治疗胰岛素抵抗的同时降低高尿酸血症可能会收到更好的临床效果。%Objective :To investigate the relationship of the type 2 diabetic patients with hyperuricemia to blood pressure and blood lipid levels .Methods :A total of 30 cases of type 2 diabetes in patients without high uric acid was Group A ,30 hyperuricemia patients without type 2 diabetes was group B ,30 patients with type 2 diabetes mellitus and hyperuricemia was group C ,Another 30 cases of healthy subjects were randomly selected from our hos-pital as a normal control group D ,All patients were measured blood pressure and lipid levels and then analyzed and compared .Results:①Compared with the normal control group ,diabetic patients without high uric acid have higher systolic blood pressure ,diastolic blood pressure ,TC ,TG and LDL-C with a statistically significant difference (P<0 .05) ,HDL-C decreased with a statistically significant difference (P<0 .05) .②Compared with the control group , the hyperuricemia patients without type 2 diabetes have elevated systolic blood pressure ,TC ,TG ,LDL-C and HDL-C decreased ,the difference was statistically significant (P <0 .05) ,but the diastolic blood pressure was without sta-tistically significant difference ( P> 0 .05 ) .③ Compared type 2 diabetes patients with hyperuricemia to normal group ,the systolic blood pressure ,diastolic blood pressure ,TC ,TG ,LDL-C were significantly increased ,and the difference is statistically significant (P <0 .05) and the lower HDL-C was statistically significant differences (P <0 .05) .④Compared type 2 diabetes mellitus patients with Hyperuricemia to type 2 diabetes patients without high u-ric acid ,the systolic blood pressure ,TC ,TG was significantly increased ,the difference was statistically significant (P <0 .05) .⑤Compared type 2 diabetes mellitus patients with Hyperuricemia to high uric acid patients without type 2 diabetes ,the systolic blood pressure ,TC ,TG was significantly increased ,the difference was statistically signifi-cant (P < 0 .05) .Conclusion:Type 2 diabetes mellitus patients with hyperuricemia have higher level in systolic blood pressure ,diastolic blood pressure ,TC ,TG ,LDL-C ,and their HDL-C are decreased .In clinical work ,com-bine the treatment of insulin resistance with reducing hyperuricemia may receive better clinical results .
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