Objective:To explore the relationship between women's HPV infection rate and ages, and the distribution of HPV subtype in Xi'an. Methods: HPV genotyping test was applied for detecting 1083 women in Xi' an. Statistics of 19 subtype detection number distribution was performed finally. The patients to be screened were divided into 6 different age groups. The positive rate was calculated respectively. The relationship between the positive rate of HPV and ages was analyzed. Results:402 positive cases were detected in 1083 cases and positive rate was 37. 12%. The positive rate of 16, 52, 58 subtypes was statistically higher than other subtypes with a total of 38. 06% , 16. 42% , 14. 43%. HPV infection positive rate and age were related and the positive rate of <20 and >60 years old was higher, respectively. But the cases of these two groups we detected were fewer than the other. The positive rate of 20~29 and 40~49 years old was higher than that in the remaining 4 groups (P<0. 05). Conclusion: The positive rate is high. HPV genotyping can detect a variety of subtypes simultaneously. The results of this study will benefit to the prevention and observation of treatment of cervical cancer.%目的:分析西安地区HPV感染亚型的分布情况及各年龄段与感染状况之间的关系.方法:采用HPV-RDB方法对1083例西安妇女进行HPV分型检测;分别统计19种亚型检出例数分布情况.将受检人群分为6个年龄阶段,分别计算其阳性检出率,分析各检出率与年龄之间的关系.结果:1083例样本中,检出HPV阳性402例,总阳性率为37.12%.亚型感染率相对较高的3个型别依次为16、52和58型,分别占检出总例数的38.06%、16.42%和14.43%.按年龄分组,以＜20组和＞60岁组检出率最高(75.00%和70.00%).剩下的4个年龄段组,以20～29岁和40～49岁年龄段检出率较高(P＜0.05).结论:西安地区HPV阳性检出率较高,应加强对宫颈癌的早期预防和早期治疗;HPV基因分型检测能同时进行多种亚型的检测,可为临床防治宫颈癌提供可靠依据.
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