Objective;To observe the curative effect and side effect of three-dimensional conformal radiotherapy ( 3D-CRT ) in the treatment of esophageal cancer. Methods: 60 cases of esophageal carcinoma patients was undertaken 3D-CRT: The position was fixed by stereo positioning frame and a negative pressure vacuum pad , and scan by spiral CT,the target volume and organs at risk sketched by the planning system of 3D-CRT, which designed and optimized the treatment regimens, that were 3~6 coplanar conformal irradiation field, 95% isodose line including the planned target volume (PTV) , 6mV X-ray linear accelerator treatment implementation, the total dose was 64~70Gy, (2Gy/f, 5f /w) , and completed in 6. 4~7 weeks. Results: 43 cases were completely remission, 57 cases were effectiveness. The local control rate of 1, 2, 3 years was, 79%, 63%, 47%. The survival rate of 1, 2, 3 year was 73% , 61% , 42%. Side effect of radiotherapy did not increase. Conclusion:Compared with traditional radiotherapy, 3D-CRT significantly enhanced the local control rate and survival rate of esophageal carcinoma as compared with traditional radiotherapy, and no more side-effect has been found.%目的:观察三维适形放疗(3D-CRT)治疗食管癌的疗效及不良反应.方法:对60例食管癌患者行3D-CRT放疗:立体定位框架及负压真空垫固定体位,螺旋CT模拟定位,三维适形放疗计划系统勾画靶区及危及器官,设计并优化治疗方案,均为3～6个共面适形照射野,95%等剂量线包括计划靶体积(PTV),6MV-X线直线加速器实施治疗,常规分割2Gy/次,5次/周,总量64～70Gy,6.4～7周完成.结果:完全缓解43例,有效57例;1、2、3年局控率分别为79%、63%、47%;1、2、3年生存率分别为73%、61%、42%;放疗不良反应无明显增加.结论:3D-CRT较常规放疗明显提高食管癌的局控率和生存率,且不增加不良反应.
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