Objective :ln order to study the healing effect of sigmoid cystoplasty in the treatment of neurogenic low compliant bladder. Methods : Six patients (5 males and 1 female) of neurogenic Low compliant bladder were given sigmoid cystoplastya and bilateral ureteral reimplantation operations. The patients' ages ranged from 16 to 40 years old and their courses of disease were from 5 to 20 years. Three of the patients had spinal cord injuries and the other three had tethered cord. Clean intermittent catheterization was carried out after the operations. Results :Follow -up observation was done on the six patients. B-ultrasonography showed the patients' hydronephrosis had relieved or disappeared after the operations. Serum creatinine levels of the patients also obviously dropped. Urodynamics showed bladder capacity was 458. 6± 37. 2 ml and the average bladder pressure at the end of filling phase of cystometry was 17. 8±4. 6cmH2O. No vesicoureteral reflux was observed. Two patients suffered urinary tract infection. One patient had intestinal mucus blockage and the symptom was relieved after treatment. Conclusion: The study shows that sigmoid cystoplasty can effectively enlarge bladder capacity, reduce the bladder pressure at the end of filling phase of cystometry, enable the patients to have a safe urine storage environment and improve the patients' life quality. In conclusion, sigmoid cystoplasty is the best method to treat neurogenic low compliant bladder.%目的:探讨乙状结肠膀胱扩大术治疗神经源性低顺应性膀胱的疗效.方法:6例神经源性低顺应性膀胱患者行乙状结肠膀胱扩大术及双侧输尿管膀胱再植术.其中脊髓损伤3例,脊髓栓系3例.术后均自行间歇清洁导尿.结果:6例患者术后B超示肾积水,较术前缓解或消失,血清肌酐水平较术前明显降低,尿动力学示膀胱容量为458.6±37.2ml,充盈期末膀胱内平均压为17.8±4.6cmH2O,无膀胱输尿管返流,2例出现泌尿系感染,1例出现肠粘液堵管,经对症治疗后缓解.结论:乙状结肠膀胱扩大术可有效地扩大膀胱容量,降低充盈期末膀胱压力,使患者有一个安全的储尿环境,是治疗神经源性低顺应性膀胱的最佳选择,提高了患者的生存质量.
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