目的：探讨糜蛋白酶联合清创术对促进III期褥疮愈合的治疗作用。方法：将近5年（2006-2011年）收集的70例III期褥疮的患者分为治疗组与对照组，在基本治疗方法不变的情况下，治疗组加用糜蛋白酶治疗，比较两组脓性分泌物坚守和消失时间。结果：治疗1周后，治疗组的效果明显高于对照组，两组差异有统计学意义。且治疗组的其他指标均有显著改善。结论：治疗III期褥疮在重视加强营养的同时，联合糜蛋白酶清创治疗褥疮明显缩短愈合时间，可推广应用。% Objective:To investigate the therapeutic effect of chymotrypsin plus debridement on the phase III bedsore healing. Methods:Seventy patients with phase III bedsore collected in recent five years (2006-2011) were divided into either a treatment group or a control group. Patients in the treatment group were additionally treated with chymotrypsin besides the basic treatment. Purulent secretions stick and disappearance time between these two groups were compared. Results:After one week treatment, the efficacy in the treatment group was significantly higher than that in the control group and the difference between them was statistically significant. Other indicators in the treatment group were significantly improved as compared with the control group. Conclusion:Combination of chymotrypsin with debridement in the treatment of the phase III bedsore can significantly shorten the healing time at the same time to strengthen nutrition.
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