Periodontitis and chronic kidney disease (CKD)are both chronic inflammatory disease.In many patients,these two kinds of disease are accompanied by immune inflammatory burden and systemic anomalies.Blood glucose,blood pressure and blood lipid ab-normalities,even the inflammation stimulus may have a significant effect on them.This paper mainly focused on the epidemiological studies of periodontitis and CKD,their common factors,the possible biological related mechanism and so on.The aim of the study is to make early disease prevention,control risk factors and reduce the risk of interaction between two diseases.It also may guide clinical treatment in order to achieve good prognosis.%牙周炎与慢性肾脏病均为慢性炎症性疾病，患者伴有全身的炎症负担及机体的免疫异常。血糖、血压、血脂等异常以及炎症的刺激对疾病有显著影响。该文主要对牙周炎与慢性肾脏病相关性的流行病学研究情况，共同的影响因素，以及可能相关的生物学机制等进行综述。旨在实现早期预防，控制危险因素，降低二者互相影响的可能性，同时指导治疗，进而达到良好的预后。
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