Is IL1R1 required for celastrol's leptin-sensitization and antiobesity effects?

Yuan Yao; Long Ma

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Is IL1R1 required for celastrol's leptin-sensitization and antiobesity effects?

机译：Celastrol的瘦素敏化和抗肥胖作用需要IL1R1吗？

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The article by Xudong Feng et al.[1], published on 4 March 2019 in the journal of Nature Medicine, showed the relationship between natural product celastrol and obesity. The researchers demonstrated celastrol was able to sensitize leptin and displayed antiobesity effects through IL1R1 (Interleukin-1 receptor 1). It was proved that IL1R1 was a gatekeeper for celastrol’s metabolic actions.

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《传统医学研究（英文版）》 |2019年第4期|174-177|共4页
作者
Yuan Yao; Long Ma;
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State Key Laboratory of Food Nutrition and Safety Key Laboratory of Industrial Fermentation Microbiology (Ministry of Education) Tianjin Key Laboratory of Industry Microbiology School of Biotechnology Tianjin University of Science&Technology Tianjin China;

State Key Laboratory of Food Nutrition and Safety Key Laboratory of Industrial Fermentation Microbiology (Ministry of Education) Tianjin Key Laboratory of Industry Microbiology School of Biotechnology Tianjin University of Science&Technology Tianjin China;

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Is IL1R1 required for celastrol's leptin-sensitization and antiobesity effects?

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