Objective: To investigate the effect of TBL pedagogy of teaching the theory of teaching specialist in biochemistry. Methods:Medical College 2012 Qujing clinical professional 129 students were randomly divided into LBL group and TBL group, after-school questionnaire and assessment. Results: Most students are satisfied with TBL teaching, TBL group scored obviously higher than LBL group. Conclusion: TBL applied biochemistry teaching, better than LBL. TBL helps to develop independent learning and comprehensive ability to promote student teamwork, biochemical theory is an effective mode of teaching, it is worth promoting.%目的：探讨TBL教学法在专科生物化学理论教学的教学效果。方法：曲靖医学高等专科学校2012级临床专业的129名学生，随机分为TBL组和LBL组，课后进行问卷调查和考核。结果：大多数学生对TBL教学满意，TBL组考试成绩得分明显高于LBL组。结论：TBL应用于生物化学教学，效果优于LBL。TBL有助于培养学生自主学习和综合能力，促进学生团队协作，是进行生物化学理论教学的有效模式，值得推广。
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