目的:观察青蒿琥酯联合奎宁马斯治疗疟疾的临床效果.方法:将180例疟疾患者根据入院顺序分为治疗组与对照组各90例,2组均给予奎宁马斯针剂静脉滴注治疗,治疗组同时给予青蒿琥酯针剂静脉滴注.结果:治疗组显效率显著高于对照组(P＜0.05),2组总有效率差异无统计学意义(P＞O.05).治疗组平均退热时间、平均原虫转阴时间均比对照组短(P＜0.05),24小时平均原虫下降率高于对照组(P＜0.05);不良反应明显少于对照组(P＜0.05).结论:青蒿琥酯联合奎宁马斯治疗疟疾疗效显著,可改善临床症状,且安全性好.%Objective: To explore clinical effects of artesunate and quinimax in treating malaria Method: All 180 patients were divided into treatment group and control group in the order of hospitalization. Both groups received intravenous quinimax injection. Threatment group were given with intravenous artesunate. Result: Effectual rate of treatment group was higher than that of control group(P<0.05), comparison of both groups showed no statistical meaning in total effective rate (P>0.05). Average time of defervescence and mean time of parasite clearance of treatment group were shorter than that of control group (P<0.05), 24 h mean decline rate of parasite of treatment group was higher than that of control group(P<0.05), Adverse reactions were remarkably less than that of control group (P<0.05). Conclusion: Artesunate and quinimax injection are effective and safe in treating malaria and could improve clinical symptoms.
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