Background: This study compares the medium-term success rate and complications of non-penetrating deep sclerectomy (NPDS) without and with autologous scleral implant in openangle glaucoma. Methods: Retrospective review of 93 eyes of 93 patients with medically uncontrolled open-angle glaucoma who underwent NPDS without (n=69, group 1) or with (n=24, group 2) autologous scleral implant. Results: The mean followupwas 16months (range 5-36) in group 1 and 15 months (range 4-28) in group 2. The mean intra-ocular pressures (IOP) preand postoperatively were, respectively, 23.8 and 16.1 mmHg in group 1, and 25.6 and 15.8 mmHg in group 2. The absolute success rate was 41%in group 1 and 54%in group 2. The qualitative success rate was 83%in group 1 and 75%in group 2. An IOP lower than 16.1 mmHg was obtained in 51%of patients in group 1 and 58%of patients in group 2. A Nd:YAGlaser goniopuncturewas performed in 30%of patients in group 1 and 50%of patients in group 2, and resulted in a better controlled IOP. Conclusions: NPDS without or with an autologous scleral implant is a safe procedure reducing the IOP significantly, but probably not sufficient when an IOP below 16 mmHg is required. We found no statistically significant difference between the two groups.
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