首页> 中文期刊> 《世界临床病例杂志》 >Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography evaluation of subcutaneous panniculitis-like T cell lymphoma and treatment response

Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography evaluation of subcutaneous panniculitis-like T cell lymphoma and treatment response

         

摘要

Subcutaneous panniculitis-like T cell lymphoma(SPTCL)is a very rare variant of non-Hodgkin’s lymphoma.Currently,there is no standard imaging method for staging of SPTCL nor for assessment of treatment response.Here,we describe our use of fluorine-18 fluorodeoxyglucose(FDG)positron emission tomography/computed tomography(PET/CT)for staging and monitoring of treatment response in 3 cases of SPTCL.Primary staging by PET/CT showed that all 3 patients had multiple foci in the subcutaneous fat tissue,with SUVmax from 10.5 to 14.6.Involvement of intra-abdominal fat with high SUVmax was identified in 2 of the patients.Use of the triple drug regimen of gemcitabine,cisplatin and methylprednisolone(commonly known as“GEM-P”)as first-line therapy or second-line therapy facilitated complete metabolic response for all 3 cases.FDG PET/CT provides valuable information for staging and monitoring of treatment response and can reveal occult involvement of the intraabdominal visceral fat.High FDG uptake on pre-treatment PET can identify patients with aggressive disease and help in selection of first-line therapy.

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