Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer

Yu Hashimoto; Tetsuo Ajiki; Hiroaki Yanagimoto; Daisuke Tsugawa; Kenta Shinozaki; Hirochika Toyama; Masahiro Kido; Takumi Fukumoto

首页> 中文期刊> 《世界临床病例杂志》 >Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer

Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer

开具论文收录证明 >>

期刊封面封底目录下载 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

BACKGROUND Radiological detection of small liver metastasis or peritoneal metastasis is still difficult,and some patients with biliary tract cancer(BTC)are unresectable after laparotomy.Staging laparoscopy may help avoid unnecessary laparotomy.However,which category of BTC is amenable with staging laparoscopy remains unclear.AIM To clarify the risk factors for occult metastasis in patients with BTC.METHODS Medical records of patients with BTC who underwent surgery at our institution between January 2008 and June 2014 were retrospectively reviewed.The patients were divided into two groups,according to resection or exploratory laparotomy(EL).Preoperative laboratory data,including inflammation-based prognostic scores and tumor markers,were compared between the two groups.Prognostic importance of detected risk factors was also evaluated.RESULTS A total of 236 patients were enrolled in this study.Twenty-six(11%)patients underwent EL.Among the EL patients,there were 16 cases of occult metastasis(7 liver metastases and 9 abdominal disseminations).Serum carcinoembryonic antigen level,carbohydrate antigen 19-9 level,neutrophil-lymphocyte ratio and modified Glasgow prognostic score were significantly higher in the EL group than in the resected group,and these factors were prognostic.Among these factors,carcinoembryonic antigen>7 ng/mL was the most useful to predict occult metastasis in BTC.When patients have more than three of these positive factors,the rate of occult metastasis increases.CONCLUSION Inflammation-based prognostic scores and tumor markers are useful in detecting occult metastasis in BTC;based on these factors,staging laparoscopy may reduce the rate of EL.

著录项

来源
《世界临床病例杂志》 |2021年第32期|P.9770-9782|共13页
作者
Yu Hashimoto; Tetsuo Ajiki; Hiroaki Yanagimoto; Daisuke Tsugawa; Kenta Shinozaki; Hirochika Toyama; Masahiro Kido; Takumi Fukumoto;
展开▼
作者单位

Department of Surgery Division of Hepato-Biliary-Pancreatic SurgeryKobe University Graduate School of Medicine Kobe Hyogo 650-0017 Japan;

Department of Surgery Division of Hepato-Biliary-Pancreatic SurgeryKobe University Graduate School of Medicine Kobe Hyogo 650-0017 Japan;

Department of Surgery Division of Hepato-Biliary-Pancreatic SurgeryKobe University Graduate School of Medicine Kobe Hyogo 650-0017 Japan;

Department of Surgery Division of Hepato-Biliary-Pancreatic SurgeryKobe University Graduate School of Medicine Kobe Hyogo 650-0017 Japan;

Department of Surgery Division of Hepato-Biliary-Pancreatic SurgeryKobe University Graduate School of Medicine Kobe Hyogo 650-0017 Japan;

Department of Surgery Division of Hepato-Biliary-Pancreatic SurgeryKobe University Graduate School of Medicine Kobe Hyogo 650-0017 Japan;

Department of Surgery Division of Hepato-Biliary-Pancreatic SurgeryKobe University Graduate School of Medicine Kobe Hyogo 650-0017 Japan;

Department of Surgery Division of Hepato-Biliary-Pancreatic SurgeryKobe University Graduate School of Medicine Kobe Hyogo 650-0017 Japan;

展开▼
原文格式 PDF
正文语种 chi
中图分类肿瘤学;
关键词
Biliary tract cancer; Staging laparoscopy; Neutrophil-lymphocyte ratio; Modified Glasgow prognostic score; Carbohydrate antigen 19-9; Carcinoembryonic antigen;

相似文献

中文文献
外文文献
专利

Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer

摘要

著录项

相似文献

相关主题

期刊订阅