The role of advanced glycation end products and their mechanism in DN

李奕茜1; 王洋2; 方朝晖3; 马建2

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The role of advanced glycation end products and their mechanism in DN

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Advanced glycation end products(AGEs), which are macromolecular material such as proteins, lipids, and nucleic acids free amino and reducing sugar on the reaction of aldehyde group under the condition of the enzyme, generate the stable compounds. AGEs formation is enhanced in diabetes and is associated with the development of diabetic complications. AGEs, as an important marker of chronic complications of diabetes mellitus, plays an important role in the development and progression of diabetic nephropathy. In the current review, we discuss mechanisms and the role of AGEs in diabetic nephropathy.

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《世界中西医结合杂志（英文）》 |2017年第3)期|P.8-11|共4页
作者
李奕茜1; 王洋2; 方朝晖3; 马建2;
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作者单位

[1]Heilongjiang University of Traditional Chinese Medicine Harbin 150000 China;

[2]The First Affiliated Hospital of Heilongjiang University of Chinese Medicine Harbin 150000 China;

[3]The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei 230000 China;

[2]The First Affiliated Hospital of Heilongjiang University of Chinese Medicine Harbin 150000 China;

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原文格式 PDF
正文语种 chi
中图分类糖尿病性昏迷及其他并发症;
关键词
高级糖基化终产物; 蛋白质; 脂质; 核酸; 化学分析;

机译：高级糖基化终产物;蛋白质;脂质;核酸;化学分析;

The role of advanced glycation end products and their mechanism in DN

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