Obstinate insomnia is common in clinic.It brings great pain to the patients and seriously affects their normal work and daily life.The author uses the traditional Chinese medicine syndrome essence to cure and heal stubborn insomnia by means of syndrome differentiation of five zang-organs from the following five aspects,which includes liver-blood deficiency, spleen afflicted with sputum dampness,deficiency of the kidney-yang, heart blood stasis and Lung Qi deficiency.This method is of significant curative effect.%顽固性失眠在临床较为常见，给患者带来了极大的痛苦，严重影响正常的生活工作。笔者运用中医辨证精化通过五脏辨证，从肝血不足、痰湿困脾、肾阳虚衰、心血瘀滞、肺气亏虚五个方面治疗疗效显著。
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