Objective To explore the correlation between senile obstructive sleep apnea hypopnea syndrome(OSAHS) and hyperlipoidemia in the elderly.Methods Prospective home -visit questionnaires were investigated on 1 868 people from November 1989 to November 2009,accompanied by annual medical examinations including blood pressure,blood -fat,serum glucose,electrocardiogram and chest x -ray.Computer tomography was carried out when hyperlipoidemia appeared,which was termination of follow -up,and the period of follow -up lasted 20 years.Results Among 1 868 people,598 /1 868(32.0%)pa-tients were definitely diagnosed of OSAHS contrasting to 1 270 /1 868(68.0%)of non -OSAHS group.Patients who developed into hyperlipoidemia were 529 /598 (88.5%)in the OSAHS group,higher than the 396 /1 270 (31.2%)in the non -OSAHS group (P <0.01).Conclusion According to longtime follow -up,the probability of OSAHS patient suffers from hyperlipoi-demia is larger than the normal.OSAHS may be an independent dangerous factor of hyperlipoidemia.%目的：随访老年人阻塞性睡眠呼吸暂停低通气综合征（OSAHS）与高脂血症的关系。方法对1868例离退休军人、老干部进行前瞻性随访，通过家访式调查，随访期间每年接受体检情况，检查血压、血脂、血糖、心电图及 X 线胸片等，随访时间为20年。结果1868例中，随访起点男性956例、女性912例，随访终点年龄73～102岁，平均年龄（79.1±5.4）岁。其中确诊 OSAHS 者32.0％（598/1868例），男性496（82.9％）例、女性102（17.1％）例；未患 OSAHS 者（对照组）1270例（68.0％）。随访终点 OSAHS 组高脂血症529（88.5％）例、对照组396例（31.2％），两组比较 P ＜0.01。结论OSAHS 患者发生高脂血症可能性高于一般人群，提示 OSAHS 可能是高脂血症的独立危险因素。
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