Purpose To describe retinotopic map ping of the visual cortex when a central scotoma is present.Design Single observational case report.Methods Scanning laser oph-thalmoscope perimetry was used to define the site and stability of fixation and the area of dense scotoma.Functional magnetic resonance imag ing of the visual cor-tex was performed while the patient v iewed an expanding annular stimulus.Results Retinoto pic mapping of the visual cortex for a patient with a horseshoe scotoma from geographic atrophy involving the ma cular region showed a loss of stimulation to the cortical a reas representing the site of the atrophic lesion.Conclusions Cortical retino-topic mapping can be performed successfully in patients with central scotomas from macular d isease.This study can serve as a basis for the future investigation of cortical plasticity in visual cortex.
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