ObjectiveTo explore the early prediction effect of penile erectile dysfunction(ED)for coronary artery disease(CAD). MethodsA total of 200 patients were divided into four groups according to their angiography results:Group 1(G1,n=59):patients with one-vessel disease(1-VD);Group 2(G2,n=40):patients with two-vessel disease(2-VD);Group 3(G3,n=50):patients with three-vessel disease(3-VD);and controls(C,n=51)without any coronary disease. The International Index of Erectile Function(IIEF)was completed for all the patients to assess their sexual function and ED.ResultsThe prevalence of ED in the CAD patients was significantly higher than that of the controls (75.16% vs. 60.8%;P=0.041). There was a significant positive correlation between the number of involved vessels in the CAD patients and ED severity(r=0.183;P=0.010). The IIEF score was negatively correlated to the number of involved vessels in the CAD patients(r=-0.216,P=0.002). ConclusionED may be considered a possible marker for the development of CAD,and provided the basis of early coronary vascular assessment for men with ED.%目的：探讨阴茎勃起功能障碍（ED）对于冠状动脉疾病（CAD）的早期预测作用。方法根据冠状动脉血管造影结果将200例患者分为4组：第1组（n=59）病变累计1支冠状动脉（1-VD）患者；第2组（n=40）：病变累计2支冠状动脉（2-VD）患者；第3组（n=50）：病变累计3支冠状动脉（3-VD）患者；对照组为无任何冠状动脉疾病（n=51）。根据国际勃起功能指数（IIEF）评估其性功能和ED严重程度。结果 CAD患者组ED患病率显著高于对照组（75.16%：60.8%；P=0.041）。ED严重程度和CAD患者受累冠状动脉支数存在显著正相关性（r=0.183，P=0.010），IIEF评分和CAD的受累冠状动脉支数之间存在显著负相关（r=-0.216，P=0.002）。结论 ED可作为CAD的一项早期预警指标，对出现ED的患者早期进行冠状动脉血管评估提供依据。
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