Objective To screen the common allergens in the region to detect and analyze the allergens in Huzhou City. Methods Carrying out retrospective analysis on the clinical data of 540 young patients suffering from allergic diseases from May 2013 to May 2015. Taking the allergen solution with physiological saline produced by German Merck Co as negative control and histamine as positive control. Results 452 cases in 540 patients showed different antigen positive,the positive rate was 83.70%,the most common allergens were dust mites,mites,cockroaches and dog headed;15.19%of the patients with allergic diseases had two kinds of allergens positive,few patients had over 3 kinds of allergens as positive. Conclusions The adolescents in Huzhou City have inhalant allergens in dust mite dermatophagoides pteronyssinus allergens,which can provide the basis for clinical diagnosis and treatment through screening and can make the patient avoid contact allergens. The distribution of allergens is different between the young and the adult. Clinical diagnosis and prevention of allergic diseases can be carried out based on the different detection rates of different age groups and common allergic diseases in different departments.%目的：通过对湖州市患过敏性疾病的青少年进行过敏原检测及分析，筛查本地区常见的过敏原。方法选取2013年5月至2015年5月就诊的540例患过敏性疾病的青少年患者临床资料进行回顾性分析。采用德国默克公司生产的变应原试液以生理盐水作阴性对照，组胺作阳性对照。结果540例患者中452例对不同抗原显示阳性，阳性率83.70%，最常见的变应原依次为粉尘螨、户主螨、狗毛、蟑螂等；有15.19%的过敏性疾病患者对2种过敏原呈阳性反应，少数患者对≥3种过敏原呈阳性反应。结论湖州市青少年人群中吸入性过敏原以粉尘螨户尘螨为主，通过过敏原筛查可为临床诊断、治疗提供依据，并可让患者避免接触相关过敏原。少年与青年人群在过敏原分布上有所差异。临床可根据各年龄段及常见过敏性疾病在不同科室检出率的不同来进行过敏性疾病的诊断和防治。
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