Objective To compare the microwave and radiofrequency ablation in the treatment of non-surgical lung malignant tumor clinical treatment effect. Methods From 1 October 2006 to 1 October 2010, 120 patients underwent computed tomography (CT)-guided percutaneous ablation of lung cancer. All patients were deemed medically inoperable. According to the sequence of admission, the patients were randomly divided into radiofrequency ablation (RFA) group and microwave ablation (MWA) group. The RFA group 75 cases, MWA 45 cases, two groups before and after treatment of 5 days on lung function in cancer treatment;Treatment situation under CT and result of the treatment were observed in the two groups. The local progression after ablation was analyzed and the treatment effect within 2 years post operation were compared between the two groups also. Results The two groups of patients with non-invasive blood pressure, heart rate, pulse, transcutaneous oxygen saturation monitoring, preoperative were stable, no statistical difference;the two groups of patients in the diameter less than 3cm patients, RFA group locating time was shorter than that of group MWA, there was a statistically significant difference between;in the diameter greater than 5cm patients, RFA group treatment time was shorter than that of group MWA, there was a statistically significant difference between;diameter greater than 3cm and less than 5cm in two patients, compared with time and location no statistically significant difference between the treatment time. Conclusion The two methods are both effective and reliable in the treatment of non-surgical lung cancer. The time of radiofrequency ablation positioning is shorter and is conducive to the treatment of cancer patients.% 目的评估射频消融及微波消融两种方法,对比在非手术性肺内恶性肿瘤(包括原发性无法手术的肺癌、肺部转移癌或复发性肺癌)的临床疗效.方法2006年10月至2010年10月无法手术的肺内恶性肿瘤患者120例,其中男90例,女30例；年龄42~76岁,平均55岁.随机分为射频消融组(RFA)75例,微波消融组(MWA)45例.对比研究两组治疗前后癌肿CT下治疗情况,及两组治疗效果的差异.结果两组患者在直径<3cm的患者中,RFA组定位时间较MWA组短,差异有统计学意义(P>0.05)；在直径>5cm的患者中,RFA组治疗时间较MWA组短,差异有统计学意义(P>0.05)；直径>3cm而<5cm的患者中,两组定位时间及治疗时间比较差异无统计学意义(P<0.05).结论采用射频消融及微波消融治疗无法手术治疗的肺内恶性肿瘤患者,两种方法疗效可靠；射频消融定位时间较短,有利于治疗肿瘤较大的患者.
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