Objective To investigate the potential applications, effects, and the outcome of transplant tissue of antilogous cartilage - cartilage membrane complex in tympanoplasty. Methods 36 cases of chronic suppurative otitis media patients with antilogous cartilage-cartilage membrane complex in tympanoplasty, follow-up after post-operation 10d, 1, 3, 6 months to 1, 2 years. Results After 10d, 32 cases healed; 1 case gap in the top of the tympanic membrane, 1 case on the bottom, 2 had infection, healed after re-operation; all cases with new tympanic membrane in 3 ～ 6 months, 2 cases the tympanic membrane become thickening and shrink plaque in 6 months to 2 years; follow up two years, all cured. Preoperative mean air conduction was ( 45.76 ±8.30 ) dB HL, bone-air conduction gap (26.15 ±8.05 ) dB HL; 1 month were ( 30.48 ±7.35 ) dB HL and ( 19.51 ±6.31 ) dB HL; 3 months were (26.08 ±7.12) dB HL and ( 12.53 ±7.69 ) dB HL; 6 months werern(23.65 ±7.60 ) dB HL and ( 10.89 ±5.42 ) dB HL respectively. Hearing significantly improved after 1 month post-operation, compared with 3 months increased (P<0.01 ) : after 6 months, 1, 2 years and 3 months were no statistically meaning ( P>0.05 ) . Conclusion Autologous cartilage - cartilage complex is an ideal material, operation supervised by convenience, easy drawing in tympanoplasty; the new tympanic membrane with normal morphology, hearing improved significantly, clinical cure rate is high.%目的 探讨自体软骨-软骨膜在中耳炎鼓室成形术中的应用、效果、移植组织的转归.方法 36例慢性化脓性中耳炎患者行软骨-软骨膜复合物鼓室成形术;术后10d,1、3、6个月,1、2年随访观察.结果 术后10d,愈合32例,鼓膜前上方、前下方出现缝隙各1例,术后感染2例,再次手术痊愈,3～6个月新鼓膜形态完整,6个月～2年2例鼓膜出现增厚、萎缩斑.随访2年成功100%;术前平均气导为(45.76±8.30)dB HL,骨气导差距为(26.15±8.05)dB HL;术后1个月为(30.48±7.35)dB HL和(19.51±6.31)dB HL;3个月为(26.08±7.12)dB HL和(12.53±7.69)dB HL;6个月为(23.65±7.60)dB HL和(10.89±5.42)dB HL.术后1个月听力较术前明显提高,术后3个月较术后1个月明显提高(P<0.01);术后6个月,1、2年与术后3个月比较差异无统计学意义(P>0.05).结论 自体软骨-软骨膜复合物,是鼓室成形术中修补鼓膜的理想材料,操作便利,取材容易;且新鼓膜形态接近正常,术后听力提高明显,临床治愈率高.
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