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Do regional variations in prevalence of cryptosporidiosis occur? The central Ohio experience.

机译:隐孢子虫病流行区域是否发生变化?俄亥俄州中部的经验。

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摘要

We screened 2,780 consecutive stool specimens submitted for routine ova and parasite examination to assess the prevalence of cryptosporidiosis in a pediatric patient population in central Ohio. The stools were prepared by formalin-ethyl acetate concentration followed by cold Kinyoun acid-fast stain of the sediment. In addition, 912 consecutive intestinal biopsies were monitored for the presence of the parasite. Cryptosporidium oocysts were found in only 0.3 per cent of stool specimens (seven specimens from three patients) and in none of the intestinal biopsies. Due to this low prevalence of cryptosporidiosis, we conclude that routine screening of stool specimens for Cryptosporidium sp. is unnecessary in our patient population. Screening should be targeted to immune compromised patients and patients with persistent diarrhea and no apparent etiology. Our study also supports the concept that there are geographic variations in the prevalence of cryptosporidiosis.
机译:我们筛选了2780份连续的粪便标本,以进行常规的卵子和寄生虫检查,以评估俄亥俄州中部儿童患者人群隐孢子虫病的患病率。通过福尔马林-乙酸乙酯浓缩,然后冷的Kinyoun抗酸染色沉淀物来制备粪便。另外,监测了912例连续的肠活检组织中是否存在寄生虫。仅在0.3%的粪便标本中发现了隐孢子虫卵囊(三名患者中有七个标本),而在肠道活检中均未发现。由于隐孢子虫病的这种低患病率,我们得出结论,常规筛查粪便样本中的隐孢子虫。在我们的患者人群中是不必要的。筛查应针对免疫功能受损的患者和持续腹泻且无明显病因的患者。我们的研究还支持隐孢子虫病患病率存在​​地理差异的概念。

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