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首页> 美国卫生研究院文献>American Journal of Public Hygiene >Early Life Conditions of Overall and Cause-Specific Mortality Among Inner-City African Americans
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Early Life Conditions of Overall and Cause-Specific Mortality Among Inner-City African Americans

机译：市区内非裔美国人的整体死亡率和特定原因死亡率的早期生活状况

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Objectives. We examined how early life conditions influence midlife overall and cause-specific mortality in a community cohort of disadvantaged African Americans.Methods. Using a prospective design, we assessed first-grade children and their teachers and families when children were 6 years old, with follow-up at ages 16, 32, and 42 years. We obtained information on death from family members, neighbors, and the National Death Index (NDI). We conducted a survival analysis and competing risk analysis to examine early life predictors of mortality.Results. Of 1242 participants, 87 (7%) had died by 2004. In multivariate Cox proportional hazards regression, males who lived in foster care and females with lower math grades in first grade were more likely to die by age 42 years. In multivariate competing risks analysis, hospitalization by the time of first grade was related to mortality from acute and chronic illness. Male gender, being in foster care, and aggressive behavior in first grade were related to mortality from drug use, violence, or suicide.Conclusions. Early classroom, environmental, and family-level interventions are potentially beneficial in reducing later overall and cause-specific mortality.
机译：目标。我们研究了处于不利地位的非裔美国人社区队列中早期生活状况如何影响中年总体死亡率和特定原因的死亡率。使用前瞻性设计，我们评估了一年级儿童及其6岁时的老师和家庭，并对16、32和42岁的孩子进行了随访。我们从家庭成员，邻居和国家死亡指数（NDI）获得了有关死亡的信息。我们进行了生存分析和竞争风险分析，以检查死亡率的早期预测指标。结果。在2004年的1242名参与者中，有87名（7％）死亡。在多因素Cox比例风险回归中，住在寄养机构中的男性和一年级数学成绩较低的女性更有可能在42岁时死亡。在多变量竞争风险分析中，一年级时的住院与急性和慢性疾病的死亡率有关。处于寄养状态的男性性别以及一年级时的攻击行为与吸毒，暴力或自杀所致的死亡有关。早期的课堂，环境和家庭层面的干预措施可能有助于降低以后的总体死亡率和因病原因导致的死亡率。

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