Quantifying the Adequacy of Opioid Analgesic Consumption Globally: An Updated Method and Early Findings

机译：量化全球阿片类镇痛药的消费量：一种更新的方法和早期发现

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Opioid analgesics are the mainstay for treatment of moderate and severe pain but, in many countries, the consumption of these medicines is inadequate. Over time, various groups have published opioid analgesic metrics, including authors from the World Health Organization. They linked consumption to a level considered adequate based on the actual consumption in developed countries.In this study, we present our current results on the adequacy of opioid analgesic consumption. We included statistics for 18 controlled opioid medicines that are primarily used as analgesics, and we developed the Adequacy of Opioid Consumption (AOC) Index. The average of the 20 most developed countries for 2015 is set as equal to an AOC Index of 100. An AOC Index of 100 or higher is considered adequate consumption.The average opioid analgesic consumption of the top-20 countries of the Human Development Index increased from 84 morphine milligram equivalents per capita (2000) to 256 morphine milligram equivalents per capita (2015). The extremes we found for 2015 were Germany (AOC Index: 304) and Nigeria (AOC Index: 0.0069). These extremes differ by 44 000 times. Adequacy of opioid analgesic consumption continues to be problematic around the world.

机译：阿片类镇痛药是中度和重度疼痛治疗的主要手段，但在许多国家，这些药物的消费量不足。随着时间的流逝，各个小组都发布了阿片类镇痛指标，包括世界卫生组织的作者。他们将消费水平与发达国家的实际消费水平相联系。在这项研究中，我们介绍了我们目前关于阿片类镇痛药消费是否足够的结果。我们纳入了主要用作镇痛药的18种受控阿片类药物的统计数据，并制定了阿片类药物消费量（AOC）指数。 2015年最发达的20个国家/地区的平均AOC指数等于100。AOC指数100或更高被认为是足够的消费。人类发展指数前20个国家/地区的阿片类镇痛药平均消费量增加了从人均84吗啡毫克当量（2000）到人均256吗啡毫克当量（2015）。我们发现2015年的极端情况是德国（AOC指数：304）和尼日利亚（AOC指数：0.0069）。这些极端相差44 000次。在世界范围内，阿片类镇痛剂的充足消费仍然是个问题。

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期刊名称 American Journal of Public Hygiene
作者
Willem K. Scholten; Ann-Eva Christensen; Anne Estrup Olesen; Asbjørn Mohr Drewes;
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作者单位

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年(卷),期 2019(109),1
年度 2019
页码 52–57
总页数 6
原文格式 PDF
正文语种
中图分类公共卫生工程;
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1. Quantifying the Adequacy of Opioid Analgesic Consumption Globally: An Updated Method and Early Findings [J] . Willem K. Scholten, Ann-Eva Christensen, Anne Estrup Olesen, American journal of public health . 2019,第1期

机译：量化全球阿片类镇痛药的消费量：一种更新的方法和早期发现
2. Quantifying the Adequacy of Opioid Analgesic Consumption Globally: An Updated Method and Early Findings [J] . Scholten Willem K., Christensen Ann-Eva, Olesen Anne Estrup, American journal of public health . 2019,第1期

机译：量化阿片类镇痛消费的充分性全球：更新的方法和早期发现
3. Adequacy of opioid analgesic consumption at country, global, and regional levels in 2010, its relationship with development level, and changes compared with 2006 [J] . DutheyB., ScholtenW. Journal of pain and symptom management. . 2014,第2期

机译：2010年国家，全球和区域各级阿片类镇痛药的消费量充足，与发展水平的关系以及与2006年相比的变化
4. UPLC-ESI+-MS/MS Method for the Quantitation of Circulating Levels of 13 Opiate and Opioid Analgesics from Dried Blood Spot Samples [C] . Melissa M. Goggin, Richard Lundberg, Karla J. Walker, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：UPLC-ESI + -MS / MS方法，用于定量从干血斑样品中定量13种阿片类药物和阿片类镇痛药的循环水平
5. Association Between Learning Methods and Analgesic Opioid Abuse [D] . Blanchard, Nicole. 2021

机译：学习方法与镇痛阿片类药物之间的关联
6. Using a Morphine Equivalence Metric to Quantify Opioid Consumption: Examining the Capacity to Provide Effective Treatment of Debilitating Pain at the Global Regional and Country Levels [O] . Aaron M. Gilson, Martha A. Maurer, Karen M. Ryan, -1

机译：使用吗啡当量度量来量化阿片类药物消费：检查能够在全球区域和国家层面进行有效治疗诽谤痛苦的能力
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Quantifying the Adequacy of Opioid Analgesic Consumption Globally: An Updated Method and Early Findings

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