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首页> 美国卫生研究院文献>BioMed Research International >Etiologic Agents of Bacterial Sepsis and Their Antibiotic Susceptibility Patterns among Patients Living with Human Immunodeficiency Virus at Gondar University Teaching Hospital, Northwest Ethiopia
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Etiologic Agents of Bacterial Sepsis and Their Antibiotic Susceptibility Patterns among Patients Living with Human Immunodeficiency Virus at Gondar University Teaching Hospital, Northwest Ethiopia

机译：埃塞俄比亚西北部贡德尔大学教学医院细菌感染脓毒症的病原体及其对人类免疫缺陷病毒患者的药敏模式

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Background. Bacterial sepsis is a major cause of illness in human immunodeficiency virus infected patients. There is scarce evidence about sepsis among HIV patients in Ethiopia. This study aimed to determine the etiologic agents of bacterial sepsis and their antibiotic susceptibility patterns among HIV infected patients. Methods. A cross-sectional study was carried out from March 1 to May 2, 2013. One hundred patients infected with HIV and suspected of having sepsis were included. Sociodemographic data were collected by interview and blood sample was aseptically collected from study participants. All blood cultures were incubated aerobically at 35°C and inspected daily for 7 days. The positive blood cultures were identified following the standard procedures and antimicrobial susceptibility testing was performed using disk diffusion technique. Data was entered by Epi-info version 3.5.1 and analysis was done using SPSS version 20. Results. Of the study participants, 31 (31%) confirmed bacterial sepsis. The major isolates were 13 (13%) Staphylococcus aureus, 8 (8%) coagulates negative staphylococci, and 3 (3%) viridans streptococci. Majority of the isolates, 25 (80.6%), were multidrug resistant to two or more antimicrobial agents. Conclusions. Bacterial sepsis was a major cause of admission for HIV infected patients predominated by Staphylococcus aureus and coagulase negative staphylococci species and most of the isolates were multidrug resistant.
机译：背景。细菌性败血症是人类免疫缺陷病毒感染患者的主要疾病原因。在埃塞俄比亚，艾滋病毒患者中很少有败血症证据。本研究旨在确定HIV感染患者中细菌性败血症的病原体及其抗生素敏感性模式。方法。 2013年3月1日至5月2日进行了横断面研究。其中包括100名感染HIV并怀疑患有败血症的患者。通过访谈收集社会人口统计学数据，并从研究参与者中无菌采集血液样本。将所有血液培养物在35°C需氧条件下孵育，每天检查7天。按照标准程序鉴定阳性血液培养物，并使用圆盘扩散技术进行抗菌药敏试验。通过Epi-info版本3.5.1输入数据，并使用SPSS版本20进行分析。结果。在研究参与者中，有31名（31％）确认了细菌性败血症。主要分离株为13个（13％）金黄色葡萄球菌，8个（8％）凝固阴性葡萄球菌和3个（3％）rid子链球菌。绝大多数分离株为25种（80.6％），对两种或多种抗菌剂具有多重耐药性。结论。细菌性败血症是主要由金黄色葡萄球菌和凝固酶阴性葡萄球菌所感染的HIV感染患者的主要原因，大多数分离株具有多重耐药性。

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