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首页> 美国卫生研究院文献>BioMed Research International >Perinatal and Neonatal Outcomes of Patients Who Were Diagnosed with Neural Tube Defect in Midtrimester Fetal Ultrasound Scan and Refused Request for Termination of Pregnancy
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Perinatal and Neonatal Outcomes of Patients Who Were Diagnosed with Neural Tube Defect in Midtrimester Fetal Ultrasound Scan and Refused Request for Termination of Pregnancy

机译：在中孕期胎儿超声检查中被诊断为神经管缺损的患者的围产期和新生儿结局，并拒绝妊娠

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Objectives. In this study, we aimed to demonstrate the perinatal and neonatal outcomes of patients who were diagnosed with neural tube defect (NTD) in the midtrimester fetal ultrasound scan and refused the request for termination of pregnancy. Material and Methods. The records of 69 patients, for whom NTD was detected in the midtrimester fetal ultrasound scan and who preferred the continuation of the pregnancy after comprehensive counselling about the possible prognosis and treatment options during the period between January 2011 and February 2016, were reviewed retrospectively. Results. Of these patients, 66.7% were 25–35 years old; 95.7% were multiparous; and 1.4% had a history of a fetus having NTD in previous pregnancies. There were 7 (10.1%) neonatal deaths in these patients. Meningomyelocele closure procedure was the most performed surgery in the postnatal period (92%). Of these patients, 30.7% had paraplegia; 51.6% had neurogenic bladder; and 6.4% had infections due to surgery. Conclusion. The results of this study demonstrated perinatal and neonatal outcomes of fetuses with NTD who were not terminated by the preference of the family in midtrimester. The experience of our centre would be beneficial as a tool for nondirective counselling of these patients when considering the antenatal/postnatal care options and postnatal prognosis.
机译：目标。在这项研究中，我们旨在证明在妊娠中期胎儿超声扫描中被诊断为神经管缺损（NTD）并拒绝终止妊娠的患者的围产期和新生儿结局。材料与方法。回顾性分析了69例在2011年1月至2016年2月期间在胎儿中期超声检查中发现NTD，并且在全面咨询可能的预后和治疗方案后倾向于继续妊娠的患者的记录。结果。在这些患者中，66.7％的年龄在25-35岁之间。 95.7％是多胎的； 1.4％的人曾有过NTD胎儿史。这些患者中有7例（10.1％）新生儿死亡。脑膜脊髓腔闭塞术是产后时期手术最多的手术（92％）。在这些患者中，有30.7％患有截瘫。 51.6％的患者患有神经源性膀胱； 6.4％因手术感染。结论。这项研究的结果表明，NTD胎儿的围产期和新生儿结局并未在中期中期被家庭偏爱所终止。考虑到产前/产后护理选择和产后预后时，我们中心的经验将成为有益于这些患者的非指导性咨询的工具。

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