• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>BMJ Global Health >Path analyses of risk factors for linear growth faltering in four prospective cohorts of young children in Ghana, Malawi and Burkina Faso
【2h】

Path analyses of risk factors for linear growth faltering in four prospective cohorts of young children in Ghana, Malawi and Burkina Faso

机译：加纳，马拉维和布基纳法索四个前瞻性队列研究线性增长步履蹒跚的危险因素的路径分析

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Stunting prevalence is an indicator of a country’s progress towards United Nations’ Sustainable Development Goal 2, which is to end hunger and achieve improved nutrition. Accelerating progress towards reducing stunting requires a deeper understanding of the factors that contribute to linear growth faltering. We conducted path analyses of factors associated with 18-month length-for-age z-score (LAZ) in four prospective cohorts of children who participated in trials conducted as part of the International Lipid-Based Nutrient Supplements Project in Ghana (n=1039), Malawi (n=684 and 1504) and Burkina Faso (n=2619). In two cohorts, women were enrolled during pregnancy. In two other cohorts, infants were enrolled at 6 or 9 months. We examined the association of 42 indicators of environmental, maternal, caregiving and child factors with 18-month LAZ. Using structural equation modelling, we examined direct and indirect associations through hypothesised mediators in each cohort. Out of 42 indicators, 2 were associated with 18-month LAZ in three or four cohorts: maternal height and body mass index (BMI). Six factors were associated with 18-month LAZ in two cohorts: length for gestational age z-score (LGAZ) at birth, pregnancy duration, improved household water, child dietary diversity, diarrhoea incidence and 6-month or 9-month haemoglobin concentration. Direct associations were more prevalent than indirect associations, but 30%–62% of the associations of maternal height and BMI with 18-month LAZ were mediated by LGAZ at birth. Factors that were not associated with LAZ were maternal iron status, illness and inflammation during pregnancy, maternal stress and depression, exclusive breast feeding during 6 months post partum, feeding frequency and child fever, malaria and acute respiratory infections. These findings may help in identifying interventions to accelerate progress towards reducing stunting; however, much of the variance in linear growth status remained unaccounted for by these 42 individual-level factors, suggesting that community-level changes may be needed to achieve substantial progress.
机译：发育迟缓的流行率表明一个国家朝着实现联合国可持续发展目标2（即消除饥饿和改善营养）的方向取得进展。加快减少发育迟缓的进程需要对导致线性增长步履蹒跚的因素有更深入的了解。我们对参与加纳国际基于脂质的营养补充剂项目（n = 1039）的一部分试验的四个前瞻性儿童队列中与18个月时长z得分（LAZ）相关的因素进行了路径分析），马拉维（n = 684和1504）和布基纳法索（n = 2619）。在两个队列中，妇女在怀孕期间入组。在另外两个队列中，婴儿在6或9个月入组。我们研究了42个环境，孕产妇，护理和儿童因素与18个月LAZ的关联。使用结构方程模型，我们通过每个队列中假设的介体检查了直接和间接关联。在42项指标中，有2项与三个或四个队列中的18个月LAZ相关：母亲身高和体重指数（BMI）。两个队列中的18个月LAZ有六个因素：胎龄z评分（LGAZ）的出生时长，怀孕持续时间，家庭用水改善，儿童饮食多样性，腹泻发生率和6个月或9个月血红蛋白浓度。直接关联比间接关联更普遍，但产妇身高和BMI与18个月LAZ的关联中，有30％–62％由出生时的LGAZ介导。与LAZ无关的因素包括孕产妇铁质状况，怀孕期间的疾病和炎症，孕产妇压力和抑郁，产后6个月内完全母乳喂养，喂养频率和儿童发烧，疟疾和急性呼吸道感染。这些发现可能有助于确定干预措施，以加快减少发育迟缓的进展；然而，线性增长状态的许多变化仍未由这42个个体水平的因素解决，这表明可能需要社区水平的改变才能取得实质性进展。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号