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首页> 美国卫生研究院文献>British Heart Journal >Quantitative thallium-201 myocardial imaging in assessing right ventricular pressure in patients with congenital heart defects.
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Quantitative thallium-201 myocardial imaging in assessing right ventricular pressure in patients with congenital heart defects.

机译：定量th 201心肌显像在评估先天性心脏病患者右室压力中的作用。

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Thallium-201 myocardial scintigraphy was performed in patients with congenital heart defects to determine whether, by quantification of right ventricular isotope uptake, one could assess the degree of right ventricular hypertrophy and so predict the level of right ventricular pressure. A total of 24 patients ranging in age from 7 months to 30 years was studied; 18 were studied before corrective surgery and six after operation. All but three had congenital heart defects which had resulted in pressure and/or volume-overload of the right ventricle. At routine cardiac catheterisation, 20 microCi/kg thallium-201 as thallous chloride was injected through the venous catheter and myocardial images were recorded in anterior and left anterior oblique projections; these were subsequently analysed quantitatively and qualitatively. Insignificant right ventricular thallium-201 counts judged as being less than 1 per cent of the injected dose or less than 0.3 of the left ventricular counts were present in six patients all with right ventricular peak systolic pressure less than 30 mmHg. In the remaining 18 patients there was a good correlation between the right ventricular/left ventricular peak systolic pressure ratio and the right ventricular/left ventricular thallium-201 counts ratio. All patients with right ventricular/left ventricular peak systolic pressure less than 0.5 had right ventricular/left ventricular thallium-201 counts less than 0.4. Qualitative evaluation of right ventricular isotope intensity proved helpful mainly in distinguishing the patients with right ventricular pressures at or above systemic levels. Thus quantitative analysis of myocardial imaging with thallium-201 is of use clinically in patients with congenital heart defects, in assessing the severity of pulmonary stenosis or the presence of pulmonary artery hypertension.
机译：先天性心脏缺陷患者进行了hall201心肌闪烁显像，以确定是否可以通过量化右心室同位素摄取量来评估右心室肥大的程度，从而预测右心室压力的水平。共研究了24例患者，年龄从7个月到30岁不等。在矫正手术前进行了18例研究，在术后进行了6例。除三个外，其他所有患者均患有先天性心脏缺陷，导致右心室压力和/或容量超负荷。在常规心脏导管插入术中，通过静脉导管注射氯化亚砜20 microCi / kg as 201，并记录前斜和左斜投影的心肌图像。随后对它们进行了定量和定性分析。在所有右室收缩压峰值均低于30 mmHg的患者中，有6例患者的右心室al 201计数微不足道，被认为小于注射剂量的1％或小于左心室计数的0.3。在其余18例患者中，右心室/左心室收缩压峰值比与右心室/左心室al 201计数比之间存在良好的相关性。所有右心室/左心室收缩压峰值低于0.5的患者的右心室/左心室th 201计数均低于0.4。右心室同位素强度的定性评估被证明主要有助于区分右心室压力处于或高于全身水平的患者。因此，在评估先天性心脏缺陷患者中，用al201进行心肌成像的定量分析可用于评估肺动脉狭窄的严重程度或肺动脉高压的存在。

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