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Validation of the beat to beat measurement of blood velocity in the human ascending aorta by a new high temporal resolution Doppler ultrasound spectral analyser

机译:新型高时间分辨率多普勒超声频谱分析仪对节拍对人升主动脉血流速度测量的验证

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摘要

Objective—To develop and validate a high temporal resolution spectral analysis system for Doppler measurements of blood velocity in the ascending aorta.Design—An observational laboratory and clinical study comparing Doppler velocity-based measurements with fluid collection, electromagnetic flow catheters and probes, and thermodilution.Setting—Tertiary referral cardiology unit and cardiac catheter laboratory.Patients—Patients undergoing routine cardiac catheterisation for ischaemic heart disease, cardiac failure, and primary pulmonary hypertension.Results—There was good agreement between Doppler-derived and electromagnetic cuff or catheter measurements of velocity in an experimental flow rig (SD of differences 4·75% for velocity integral) and in the patients (SD of differences 4% for velocity integral). There was also reasonably good agreement between simultaneous Doppler-derived and thermodilution-estimated cardiac output measurements in patients undergoing cardiac catheterisation (SD of differences 12·6%).Conclusions—This new method of high temporal resolution spectral analysis improves the resolution of rapidly changing blood velocities and may improve the ability to describe blood velocity patterns in the ascending aorta.
机译:目的-开发和验证用于多普勒测量升主动脉血流速度的高分辨光谱分析系统。设计-观察实验室和临床研究,将基于多普勒速度的测量与流体收集,电磁流导管和探头以及热稀释进行比较设置-第三级转诊心脏病科和心脏导管实验室。患者-接受常规心脏导管插入术治疗的缺血性心脏病,心力衰竭和原发性肺动脉高压患者。在实验型流动装置中(速度积分的SD差异为4·75%)和在患者中(速度积分的SD差异为4%)。在进行心脏导管插入术的患者中,同时进行多普勒推导和热稀释估算的心输出量之间也有相当好的一致性(SD的差异为12·6%)。血流速度,可能会提高描述升主动脉血流速度模式的能力。

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