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首页> 美国卫生研究院文献>British Journal of Industrial Medicine >Historical limitations of determinant based exposure groupings in the rubber manufacturing industry
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Historical limitations of determinant based exposure groupings in the rubber manufacturing industry

机译：橡胶制造业中基于行列式的暴露组的历史局限性

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>Aims: To study the validity of using a cross-sectional industry-wide exposure survey to develop exposure groupings for epidemiological purposes that extend beyond the time period in which the exposure data were collected. >Methods: Exposure determinants were used to group workers into high, medium, and low exposure groups. The contrast of this grouping and other commonly used grouping schemes based on plant and department within this exposure survey and a previously conducted survey within the same industry (and factories) were estimated and compared. >Results: Grouping of inhalable and dermal exposure based on exposure determinants resulted in the highest, but still modest, contrast (ε ∼ 0.3). Classifying subjects based on a combination of plant and department resulted in a slightly lower contrast (ε ∼ 0.2). If the determinant based grouping derived from the 1997 exposure survey was used to classify workers in the 1988 survey the average contrast decreased significantly for both exposures (ε ∼ 0.1). On the contrary, the exposure classification based on plant and department increased in contrast (from ε ∼ 0.2 to ε ∼ 0.3) and retained its relative ranking overtime. >Conclusions: Although determinant based groupings seem to result in more efficient groupings within a cross-sectional survey, they have to be used with caution as they might result in significant less contrast beyond the studied population or time period. It is concluded that a classification based on plant and department might be more desirable for retrospective studies in the rubber manufacturing industry, as they seem to have more historical relevance and are most likely more accurately recorded historically than information on exposure determinants in a particular industry.
机译：>目标：研究使用横断面全行业暴露调​​查为流行病学目的开发暴露分组的有效性，这些分组超出了收集暴露数据的时间范围。 >方法：暴露因素用于将工人分为高，中和低暴露组。估算并比较了此暴露调查中基于工厂和部门的此分组与其他常用分组方案以及同一行业（和工厂）之前进行的调查的对比。 >结果：根据接触决定因素对可吸入和皮肤接触进行分组可得出最高但仍中等的对比度（ε〜0.3）。根据工厂和部门的组合对主题进行分类会导致对比度略低（ε〜0.2）。如果从1997年暴露调查得出的基于决定因素的分组在1988年调查中用于对工人进行分类，则两次暴露的平均对比显着降低（ε〜0.1）。相反，基于工厂和部门的暴露分类在对比度上有所提高（从ε〜0.2到ε〜0.3），并且随着时间的推移保持了相对排名。 >结论：尽管基于行列式的分组似乎可以使横断面调查中的分组更为有效，但必须谨慎使用，因为它们可能导致超出研究人群或时间段的对比度明显降低。结论是，对于橡胶制造行业的回顾性研究，基于工厂和部门的分类可能更合乎需要，因为与特定行业的暴露决定因素信息相比，它们似乎具有更多的历史关联性，并且最有可能在历史上更准确地记录下来。

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