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Improving planning design reporting and scientific quality of animal experiments by using the Gold Standard Publication Checklist in addition to the ARRIVE guidelines

机译:除了ARRIVE准则外还通过使用黄金标准出版物清单来改善动物实验的计划设计报告和科学质量

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摘要

Several studies have demonstrated serious omissions in the way research that use animals is reported. In order to improve the quality of reporting of animal experiments, the Animals in research: reporting in vivo experiments (ARRIVE) Guidelines were published in the British Journal of Pharmacology in August 2010.However, not only the quality of reporting of completed animal studies needs to be improved, but also the design and execution of new experiments. With both these goals in mind, we published the Gold Standard Publication Checklist (GSPC) in May 2010, a few months before the ARRIVE guidelines appeared. In this letter, we compare the GSPC checklist with the ARRIVE Guidelines. The GSPC describes certain items in more detail, which makes it both easier to use when designing and conducting an experiment and particularly suitable for making systematic reviews of animal studies more feasible. In order to improve not only the reporting but also the planning, design, execution and thereby, the scientific quality of animal experiments, we strongly recommend to all scientists involved in animal experimentation and to editors of journals publishing animal studies to take a closer look at the contents of both the ARRIVE guidelines and GSPC, and select the set of guidelines which is most appropriate for their particular situation.LINKED ARTICLESTo view the article by Kilkenny et al. visit . To view the editorial by McGrath et al. visit
机译:多项研究表明,在报道使用动物的研究方法中存在严重的遗漏。为了提高动物实验报告的质量,2010年8月在《英国药理学杂志》(British Journal of Pharmacology)上发表了《动物研究:体内实验报告(ARRIVE)指南》,但不仅需要完整的动物研究报告质量有待改进,而且还要设计和执行新的实验。考虑到这两个目标,我们在ARRIVE指南出台前几个月就于2010年5月发布了黄金标准出版物清单(GSPC)。在这封信中,我们将GSPC清单与ARRIVE指南进行了比较。 GSPC更详细地描述了某些项目,这使得在设计和进行实验时更容易使用,并且特别适合使动物研究的系统评价更加可行。为了不仅改善报告的质量,而且还改善动物实验的计划,设计,执行以及科学质量,我们强烈建议所有参与动物实验的科学家和出版动物研究期刊的编辑们仔细研究一下结合ARRIVE指南和GSPC的内容,并选择最适合其特定情况的一组指南。链接的文章以查看Kilkenny等人的文章。参观。要查看McGrath等人的社论。访问

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