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首页> 美国卫生研究院文献>British Medical Journal >Screening for squamous cervical cancer: duration of low risk after negative results of cervical cytology and its implication for screening policies. IARC Working Group on evaluation of cervical cancer screening programmes.
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Screening for squamous cervical cancer: duration of low risk after negative results of cervical cytology and its implication for screening policies. IARC Working Group on evaluation of cervical cancer screening programmes.

机译：宫颈鳞癌的筛查：宫颈细胞学阴性结果后低危持续时间及其对筛查政策的意义。 IARC子宫颈癌筛查计划评估工作组。

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摘要

A collaborative study of screening programmes in eight countries was performed to estimate the risks of cervical cancer associated with different screening policies. Most of the data came from centrally organised screening programmes. Relative protection was higher in women who had had two or more negative results of screening tests than in those who had had only one negative smear, particularly in the first five years after the last test. There was little difference in the protection afforded by screening every year compared with every three years, but screening only once every five or 10 years offered appreciably less protection. The age of the women did not affect the sensitivity of the test or the sojourn time of the disease (the length of the detectable preclinical phase during which abnormal cytology could be picked up if a smear were taken); invasive cancer in women under 25 was rare. Centrally organised screening programmes were more effective than uncoordinated screening. Screening programmes should be aimed principally at women aged 35-60 but should start some years before the age of 35, and the intervals between screening should be three years or less.
机译：在八个国家进行了一项筛查计划的合作研究，以评估与不同筛查政策相关的宫颈癌风险。大多数数据来自中央组织的筛查计划。筛查结果阴性两次以上的女性，相对于仅有一次涂片阴性的女性，相对保护性更高，尤其是在上次检查后的头五年。与每三年进行一次筛查相比，每年进行筛查所提供的保护几乎没有什么不同，但是每五到十年仅筛查一次所提供的保护就少得多。妇女的年龄不影响测试的敏感性或疾病的停留时间（可检测到的临床前阶段的长度，如果进行涂片检查则可在该阶段进行异常细胞学检查）； 25岁以下女性的浸润癌很少见。集中组织的筛查计划比不协调的筛查更有效。筛查计划应主要针对35至60岁的女性，但应在35岁之前的几年开始，筛查之间的间隔应为三年或更短。

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  • 期刊名称 British Medical Journal
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  • 年(卷),期 1986(293),6548
  • 年度 1986
  • 页码 659–664
  • 总页数 6
  • 原文格式 PDF
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