• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>British Medical Journal >Strategies for reducing coronary risk factors in primary care: which is most cost effective?
【2h】

Strategies for reducing coronary risk factors in primary care: which is most cost effective?

机译：减少基层医疗中冠心病危险因素的策略：哪种最具成本效益？

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE--To examine the relative cost effectiveness of a range of screening and intervention strategies for preventing coronary heart disease in primary care. SUBJECTS--7840 patients aged 35-64 years who were participants in a trial of modifying coronary heart disease risk factors in primary care. DESIGN--Effectiveness of interventions assumed and the potential years of life gained estimated from a risk equation calculated from Framingham study data. MAIN OUTCOME MEASURE--The cost per year of life gained. RESULTS--The most cost effective strategy was minimal screening of blood pressure and personal history of vascular disease, which cost 310 pounds-930 pounds per year of life gained for men and 1100 pounds-3460 pounds for women excluding treatment of raised blood pressure. The extra cost per life year gained by adding smoking history to the screening was 400 pounds-6300 pounds in men. All strategies were more cost effective in men than in women and more cost effective in older age groups. Lipid lowering drugs accounted for at least 70% of the estimated costs of all strategies. Cost effectiveness was greatest when drug treatment was limited to those with cholesterol concentrations above 9.5 mmol/l. CONCLUSIONS--Universal screening and intervention strategies are an inefficient approach to reducing the coronary heart disease burden. A basic strategy for screening and intervention, targeted at older men with raised blood pressure and limiting the use of cholesterol lowering drugs to those with very high cholesterol concentrations would be most cost effective.
机译：目的-研究预防初级保健中冠心病的一系列筛查和干预策略的相对成本效益。受试者--7840岁，年龄在35-64岁之间，他们参加了改善初级保健中冠心病危险因素的试验。设计-根据Framingham研究数据计算出的风险方程式，假设了干预措施的有效性和获得的潜在寿命。主要观察指标-每年增加的生命成本。结果-最具成本效益的策略是对血压和个人血管病史进行最少筛查，其中不包括高血压治疗的男性每年花费310磅至930磅，女性每年花费1100磅至3460磅。通过在筛查中增加吸烟史，男性每生下来的额外费用为400磅至6300磅。所有策略在男性中比在女性中更具成本效益，在老年群体中更具成本效益。降脂药物至少占所有策略估计费用的70％。当药物治疗仅限于胆固醇浓度高于9.5 mmol / l的药物时，成本效益最大。结论：普遍的筛查和干预策略是降低冠心病负担的一种无效方法。针对血压升高且将降胆固醇药物的使用仅限于胆固醇浓度很高的男性的基本筛查和干预策略，将是最具成本效益的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号