Methods of molecular analysis: assessing losses and gains in tumours

机译：分子分析方法：评估肿瘤的损失和增加

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The study of chromosomal aberrations has facilitated the understanding of tumorigenesis. By applying molecular genetic techniques to regions highlighted by cytogenetic study, many genes important in tumorigenesis have been identified. This review will describe the cytogenetic and molecular cytogenetic techniques used to identify these changes. The clinical information that they can provide, including diagnostic and prognostic information, will also briefly be discussed.

机译：染色体畸变的研究促进了对肿瘤发生的理解。通过将分子遗传学技术应用于细胞遗传学研究突出的区域，已鉴定出许多在肿瘤发生中重要的基因。这篇综述将描述用于鉴定这些变化的细胞遗传学和分子细胞遗传学技术。他们将提供的临床信息（包括诊断和预后信息）也将进行简要讨论。

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期刊名称 Clinical Molecular Pathology
作者
R Roylance;
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作者单位

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年(卷),期 2002(55),1
年度 2002
页码 25–28
总页数 4
原文格式 PDF
正文语种
中图分类病理学;
关键词
cytogenetics fluorescence in situ hybridisation comparative genomic hybridisation;

机译：细胞遗传学;荧光原位杂交;比较基因组杂交;

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Methods of molecular analysis: assessing losses and gains in tumours

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