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首页> 美国卫生研究院文献>Current Controlled Trials in Cardiovascular Medicine >A multi-site single blind clinical study to compare the effects of prolonged exposure eye movement desensitization and reprocessing and waiting list on patients with a current diagnosis of psychosis and co morbid post traumatic stress disorder: study protocol for the randomized controlled trial Treating Trauma in Psychosis
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A multi-site single blind clinical study to compare the effects of prolonged exposure eye movement desensitization and reprocessing and waiting list on patients with a current diagnosis of psychosis and co morbid post traumatic stress disorder: study protocol for the randomized controlled trial Treating Trauma in Psychosis

机译：多地点单盲临床研究比较长期暴露眼球运动减敏再加工和等待名单对当前诊断为精神病和合并精神创伤后应激障碍的患者的影响：随机对照试验治疗创伤的研究方案精神病

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BackgroundTrauma contributes to psychosis and in psychotic disorders post-traumatic stress disorder (PTSD) is often a comorbid disorder. A problem is that PTSD is underdiagnosed and undertreated in people with psychotic disorders. This study’s primary goal is to examine the efficacy and safety of prolonged exposure and eye movement desensitization and reprocessing (EMDR) for PTSD in patients with both psychotic disorders and PTSD, as compared to a waiting list. Secondly, the effects of both treatments are determined on (a) symptoms of psychosis, in particular verbal hallucinations, (b) depression and social performance, and (c) economic costs. Thirdly, goals concern links between trauma exposure and psychotic symptomatology and the prevalence of exposure to traumatic events, and of PTSD. Fourthly predictors, moderators, and mediators for treatment success will be explored. These include cognitions and experiences concerning treatment harm, credibility and burden in both participants and therapists.
机译：背景创伤导致精神病，并且在精神病中，创伤后应激障碍（PTSD）通常是合并症。问题在于精神病患者的PTSD诊断不足和治疗不足。这项研究的主要目的是与精神病患者和候补患者相比，研究长期暴露以及眼睛运动脱敏和再加工（EMDR）对精神病和PTSD患者的疗效和安全性。其次，两种治疗的效果取决于（a）精神病症状，尤其是口头幻觉，（b）抑郁和社会表现，以及（c）经济成本。第三，目标关注创伤暴露与精神病症状学，创伤事件和PTSD患病率之间的联系。第四，将探讨治疗成功的预测因素，调节者和中介者。这些包括参与者和治疗师对治疗危害，信誉和负担的认知和经验。

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