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首页> 美国卫生研究院文献>International Journal of Environmental Research and Public Health >Hydration Fluid Intake and Related Urine Biomarkers among Male College Students in Cangzhou China: A Cross-Sectional Study—Applications for Assessing Fluid Intake and Adequate Water Intake
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Hydration Fluid Intake and Related Urine Biomarkers among Male College Students in Cangzhou China: A Cross-Sectional Study—Applications for Assessing Fluid Intake and Adequate Water Intake

机译：沧州男大学生水合摄水量及相关尿液生物标志物的跨学科研究-评估摄水量和充足水量的应用

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The objectives of this study were to assess the associations between fluid intake and urine biomarkers and to determine daily total fluid intake for assessing hydration status for male college students. A total of 68 male college students aged 18–25 years recruited from Cangzhou, China completed a 7-day cross-sectional study. From day 1 to day 7; all subjects were asked to complete a self-administered 7-day 24-h fluid intake record. The foods eaten by subjects were weighed and 24-h urine was collected for three consecutive days on the last three consecutive days. On the sixth day, urine osmolality, specific gravity (USG), pH, and concentrations of potassium, sodium, and chloride was determined. Subjects were divided into optimal hydration, middle hydration, and hypohydration groups according to their 24-h urine osmolality. Strong relationships were found between daily total fluid intake and 24-h urine biomarkers, especially for 24-h urine volume (r = 0.76; p < 0.0001) and osmolality (r = 0.76; p < 0.0001). The percentage of the variances in daily total fluid intake (R2) explained by PLS (partial least squares) model with seven urinary biomarkers was 68.9%; two urine biomarkers—24-h urine volume and osmolality—were identified as possible key predictors. The daily total fluid intake for assessing optimal hydration was 2582 mL, while the daily total fluid intake for assessing hypohydration was 2502 mL. Differences in fluid intake and urine biomarkers were found among male college students with different hydration status. A strong relationship existed between urine biomarkers and fluid intake. A PLS model identified that key variables for assessing daily total fluid intake were 24-h urine volume and osmolality. It was feasibility to use total fluid intake to judge hydration status.
机译：这项研究的目的是评估液体摄入量与尿液生物标志物之间的联系，并确定每日总液体摄入量以评估男大学生的水合作用状况。从中国沧州招募的68名18-25岁的男大学生完成了为期7天的横断面研究。从第1天到第7天；所有受试者均被要求填写一份自我管理的7天24小时液体摄入记录。称重受试者所吃的食物，并在连续的三天内连续三天收集24小时尿液。在第六天，测定尿渗透压，比重（USG），pH以及钾，钠和氯化物的浓度。根据受试者的24小时尿渗透压，将其分为最佳水合作用，中水合作用和低水合作用组。发现每日总液体摄入量与24小时尿液生物标志物之间存在密切关系，尤其是对于24小时尿液量（r = 0.76; p <0.0001）和重量克分子渗透压浓度（r = 0.76; p <0.0001）。用具有七个尿液生物标志物的PLS（偏最小二乘）模型解释的每日总液体摄入量（R 2 ）的变化百分比为68.9％；确定了两个尿液生物标志物（24小时尿量和重量克分子渗透压摩尔浓度）是可能的关键预测指标。评估最佳水合作用的每日总液体摄入量为2582 mL，而评估低水合作用的每日总液体摄入量为2502 mL。在水化程度不同的男大学生中，液体摄入量和尿液生物标志物存在差异。尿液生物标志物与液体摄入之间存在密切关系。 PLS模型确定，评估每日总液体摄入量的关键变量是24小时尿量和重量克分子渗透压浓度。使用总液体摄入量来判断水合状态是可行的。

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