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首页> 美国卫生研究院文献>International Journal of Environmental Research and Public Health >Respiratory Symptoms in Relation to Living near a Crude Oil First Treatment Plant in Italy: A Cross-Sectional Study
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Respiratory Symptoms in Relation to Living near a Crude Oil First Treatment Plant in Italy: A Cross-Sectional Study

机译：与意大利原油优先处理厂附近生活有关的呼吸道症状：跨部门研究

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Exposure to air pollution has been shown to increase the risk of developing chronic respiratory diseases. The largest crude oil first treatment plant in Italy emits harmful polluting substances. This cross-sectional study assesses the occurrence of respiratory symptoms in a sample of the adult population living near the plant. A proximal and a reference area were defined in order to recruit 200 subjects. Each subject performed a spirometry test and completed a questionnaire. Associations between the distance from the plant and selected respiratory outcomes were assessed (distance-based approach). The prevalence of outcomes between a proximal and a reference area (area-based approach) were also compared. Odds ratios were adjusted for potential confounders. Living near the plant was associated with a higher prevalence of respiratory symptoms, with significant associations for severe dyspnoea equivalent to the halving of risk as the distance of residence from the plant increased by 1 km (adjusted odds ratio (OR) 0.48, confidence interval at the 95% probability level (95% CI): 0.25–0.92). Several signals emerged for respiratory allergic symptoms. The area-based approach generally confirmed the results obtained with the distance-based approach. This is the first study to be carried out on a crude oil first treatment plant aimed at assessing the association with the occurrence of respiratory symptoms. These findings contribute to the evidence supporting the need for a space–time surveillance system in the investigated area.
机译：事实证明，暴露于空气污染中会增加患慢性呼吸道疾病的风险。意大利最大的原油第一处理厂排放有害污染物质。这项横断面研究评估了居住在植物附近的成年人口样本中呼吸道症状的发生。定义了近端区域和参考区域，以招募200名受试者。每个受试者进行肺活量测定测试并填写问卷。评估了距植物的距离与选定的呼吸结果之间的关联（基于距离的方法）。还比较了近端和参考区域之间的结局患病率（基于区域的方法）。针对潜在混杂因素调整了赔率。居住在工厂附近与呼吸系统症状的患病率较高相关，严重呼吸困难的显着相关性相当于风险的一半，因为距工厂的居住距离增加了1 km（校正比值比（OR）0.48，置信区间为95％的概率水平（95％CI）：0.25–0.92）。对于呼吸道过敏症状出现了几种信号。基于面积的方法通常证实了基于距离的方法获得的结果。这是首次在原油优先处理厂进行的研究，旨在评估与呼吸道症状发生的关系。这些发现有助于提供证据支持在研究区域建立时空监视系统。

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