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Depression and Quality of Life among Patients Living with HIV/AIDS in the Era of Universal Treatment Access in Vietnam

机译:越南普及治疗时代艾滋病毒/艾滋病患者的抑郁和生活质量

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摘要

Although antiretroviral treatment (ART) access has been universal in recent years, few studies have examined if this policy contributes to the mental health of the patients. This study assessed depression and its relations with health-related quality of life (HRQOL), which is defined as the status of general well-being, physical, emotional, and psychological, among HIV patients. A cross-sectional study was conducted in 482 patients at five outpatient clinics. Patient Health Questionnaire-9 (PHQ-9) and EuroQol-5 dimensions-5 levels (EQ-5D-5L) were used to assess the severity of depression and HRQOL. About one-fifth of patients reported symptoms of depression. According to the result of a multivariate logistic regression model, patients who had a lower number of CD4 cells at the start of ART, who received ART in the clinic without HIV counseling and testing (HCT) services, who had a physical health problem, and who experienced discrimination were more likely to have depression. Depression was associated with significantly decreased HRQOL. Depression is prevalent and significantly negatively associated with HRQOL of HIV/AIDS patients. We recommend screening for depression and intervening in the lives of depressed individuals with respect to those who start ART late, and we also recommend community-based behavioral change campaigns to reduce HIV discrimination.
机译:尽管近年来抗逆转录病毒治疗(ART)的普及已经普及,但很少有研究检查这种政策是否有助于患者的心理健康。这项研究评估了抑郁症及其与健康相关生活质量(HRQOL)的关系,HRQOL被定义为HIV患者的总体健康,身体,情感和心理状况。在五个门诊诊所对482例患者进行了横断面研究。患者健康问卷9(PHQ-9)和EuroQol-5维度5水平(EQ-5D-5L)用于评估抑郁症和HRQOL的严重程度。大约五分之一的患者报告有抑郁症状。根据多因素Logistic回归模型的结果,在ART开始时CD4细胞数量较少的患者,在没有HIV咨询和检测(HCT)服务的情况下在诊所接受ART治疗,并且存在身体健康问题;以及遭受歧视的人更容易患上抑郁症。抑郁与HRQOL显着降低有关。抑郁症很普遍,与HIV / AIDS患者的HRQOL呈显着负相关。我们建议对那些较晚开始接受抗逆转录病毒疗法的人进行抑郁症筛查,并干预抑郁症患者的生活,我们还建议开展基于社区的行为改变运动,以减少艾滋病毒的歧视。

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