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首页> 美国卫生研究院文献>International Journal of General Medicine >Polymyalgia rheumatica in a married couple
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Polymyalgia rheumatica in a married couple

机译：风湿性多肌痛已婚夫妇

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摘要

The case of a married couple developing polymyalgia rheumatica (PMR) consecutively is presented. The 55-year-old wife complained in June 2010 about pain in her neck. Case history, physical examination, and erythrocyte sedimentation rate (ESR) of 80 mm/hour led to the diagnosis of PMR. In May 2011, her 66-year old husband complained about pain in his neck, shoulders, buttocks, and thighs. Considering anamnesis, physical examination, and ESR of 56 mm/hour, the diagnosis of PMR was made. Both wife and husband responded to steroid treatment. When the steroid dose was gradually reduced, both patients relapsed. In order to lower the cumulative dose of glucocorticoid therapy, 10 mg methotrexate per week was added. In the literature, six cases of polymyalgia rheumatica in married couples have been described to date. In four cases, polymyalgia rheumatica occurred first in the wife. The interval of the diagnosis between the spouses ranged from 0 to 89 months. Although in most of the previous case reports a genetic disposition and an infectious agent have been discussed, this hypothesis must be questioned.
机译：介绍了一对已发展为风湿性多肌痛（PMR）的已婚夫妇的病例。这位55岁的妻子在2010年6月抱怨脖子疼痛。病史，体格检查和80毫米/小时的红细胞沉降率（ESR）导致对PMR的诊断。 2011年5月，她66岁的丈夫抱怨脖子，肩膀，臀部和大腿疼痛。考虑到记忆检查，体格检查和ESR为56 mm /小时，对PMR进行了诊断。妻子和丈夫都对类固醇治疗有反应。当类固醇剂量逐渐减少时，两名患者均复发。为了降低糖皮质激素治疗的累积剂量，每周添加10 mg氨甲蝶呤。在文献中，迄今已描述了六例已婚夫妇的风湿性多肌痛。在四例中，风湿性多肌痛首先发生在妻子身上。配偶之间的诊断间隔为0到89个月。尽管在大多数以前的病例报告中都讨论了遗传因素和传染原，但必须质疑这一假设。

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