首页> 美国卫生研究院文献>International Journal of Clinical and Experimental Medicine >Postoperative continuous wound infusion of ropivacaine has comparable analgesic effects and fewer complications as compared to traditional patient-controlled analgesia with sufentanil in patients undergoing non-cardiac thoracotomy
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Postoperative continuous wound infusion of ropivacaine has comparable analgesic effects and fewer complications as compared to traditional patient-controlled analgesia with sufentanil in patients undergoing non-cardiac thoracotomy

机译:与接受舒芬太尼的传统患者自控镇痛相比非心脏开胸手术后罗哌卡因术后连续伤口输注具有可比的镇痛效果并且并发症更少

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摘要

Objective: To compare the postoperative analgesic effects of continuous wound infusion of ropivacaine with traditional patient-controlled analgesia (PCA) with sufentanil after non-cardiac thoracotomy. Methods: One hundred and twenty adult patients undergoing open thoracotomy were recruited into this assessor-blinded, randomized study. Patients were randomly assigned to receive analgesia through a wound catheter placed below the fascia and connected to a 2 ml/h ropivacaine 0.5% (RWI group) or sufentanil PCA (SPCA group). Analgesia continued for 48 h. Visual analogue scores (VAS) at rest and movement, Ramsay scores and adverse effects were recorded at 2, 8, 12, 24, 36 and 48 h after surgery. Three months after discharge, patient’s satisfaction, residual pain and surgical wound complications were assessed. Results: General characteristics of patients were comparable between two groups. There were no statistical differences in the VAS scores and postoperative pethidine consumption between two groups (P > 0.05). However, when compared with SPCA group, the incidences of drowsiness, dizziness and respiratory depression, ICU stay and hospital expenditure reduced significantly in RWI group (P < 0.05). Patients’ satisfaction with pain management was also improved markedly in RWI group (P < 0.05). Conclusion: Continuous wound infusion with ropivacaine is effective for postoperative analgesia and has comparable effects to traditional PCA with sufentanil. Furthermore, this therapy may also reduce the incidences of drowsiness, dizziness, respiratory depression and decrease the ICU stay and hospital expenditure.
机译:目的:比较非心脏开胸术后连续输注罗哌卡因与传统患者自控镇痛(PCA)联合舒芬太尼的术后镇痛效果。方法:将120例行开胸手术的成人患者纳入该评估者盲目的随机研究。患者被随机分配通过位于筋膜下方的创口导管接受镇痛,并与2 ml / h 0.5%罗哌卡因(RWI组)或舒芬太尼PCA(SPCA组)连接。镇痛持续48小时。在手术后2、8、12、24、36和48小时记录静止和运动时的视觉模拟评分(VAS),Ramsay评分和不良反应。出院三个月后,评估患者的满意度,残余疼痛和手术伤口并发症。结果:两组患者的一般特征相当。两组之间的VAS评分和术后哌替啶用量无统计学差异(P> 0.05)。然而,与SPCA组相比,RWI组的嗜睡,头晕和呼吸抑制,ICU住院时间和住院费用的发生率显着降低(P <0.05)。 RWI组患者对疼痛管理的满意度也显着提高(P <0.05)。结论:罗哌卡因连续伤口输注对术后镇痛是有效的,并且具有与舒芬太尼传统PCA相当的疗效。此外,这种疗法还可以减少嗜睡,头晕,呼吸抑制的发生,并减少重症监护病房的住院时间和住院费用。

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