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首页> 美国卫生研究院文献>International Archives of Otorhinolaryngology >Vocal Cord Dysfunction: Analysis of 27 Cases and Updated Review of Pathophysiology Management
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Vocal Cord Dysfunction: Analysis of 27 Cases and Updated Review of Pathophysiology Management

机译：声带功能障碍：27例分析和病理生理学和管理的最新审查。

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>Introduction  Vocal cord dysfunction is characterized by unintentional paradoxical vocal cord movement resulting in abnormal inappropriate adduction, especially during inspiration; this predominantly manifests as unresponsive asthma or unexplained stridor. It is prudent to be well informed about the condition, since the primary presentation may mask other airway disorders. >Objective  This descriptive study was intended to analyze presentations of vocal cord dysfunction in a tertiary care referral hospital. The current understanding regarding the pathophysiology and management of the condition were also explored. >Methods  A total of 27 patients diagnosed with vocal cord dysfunction were analyzed based on demographic characteristics, presentations, associations and examination findings. The mechanism of causation, etiological factors implicated, diagnostic considerations and treatment options were evaluated by analysis of the current literature. >Results  There was a strong female predilection noted among the study population ( n  = 27), which had a mean age of 31. The most common presentations were stridor (44%) and refractory asthma (41%). Laryngopharyngeal reflux disease was the most common association in the majority (66%) of the patients, with a strong overlay of anxiety, demonstrable in 48% of the patients. >Conclusion  Being aware of the condition is key to avoid misdiagnosis in vocal cord dysfunction. Fiberoptic laryngoscopy is the diagnostic gold standard to demonstrate paradoxical vocal cord adduction during an attack. A multidisciplinary approach should be adapted for the management, which should be specific and tailored for individual patients.
机译：>简介声带功能障碍的特征是意外的声带运动异常，导致异常的不适当内收，尤其是在吸气期间；这主要表现为哮喘无反应或喘鸣。由于主要表现可能掩盖其他气道疾病，因此应谨慎告知有关情况。 >目的这项描述性研究旨在分析三级转诊医院声带功能障碍的表现。还探讨了有关病理生理学和疾病控制的当前理解。 >方法根据人口统计学特征，表现，关联和检查结果，对27位诊断为声带功能障碍的患者进行了分析。通过对现有文献的分析，评估了病因机制，病因，诊断和治疗方案。 >结果在研究人群中有强烈的女性偏爱（n = 27），平均年龄为31岁。最常见的表现是喘鸣（44％）和难治性哮喘（41％） 。喉咽反流病是大多数患者（66％）中最常见的关联，伴有强烈的焦虑感，在48％的患者中可证实。 >结论了解病情是避免误诊声带功能障碍的关键。纤维喉镜检查是诊断发作时声带内收异常的诊断金标准。应针对管理采用多学科方法，该方法应针对具体患者并针对其量身定制。

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