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Functional characteristics of intraepithelial lymphocytes from mouse small intestine. III. Inability of intraepithelial lymphocytes to induce a systemic graft-versus-host reaction is because of failure to migrate in vivo.

机译：小鼠小肠上皮内淋巴细胞的功能特性。三上皮内淋巴细胞不能诱导全身性移植物抗宿主反应是由于不能在体内迁移。

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In this study we have investigated whether addition of bone marrow accessory cells or concurrent administration of recombinant IL-2 would allow intraepithelial lymphocytes (IEL) to induce a systemic, lethal GvHR in irradiated hosts. In addition we have studied the ability of IEL to migrate into lymphoid tissues after intravenous injection and compared this with their locomotor capacity in vitro.

机译：在这项研究中，我们研究了添加骨髓辅助细胞或同时给予重组IL-2是否会使上皮内淋巴细胞（IEL）在受辐照的宿主中诱导全身性致死性GvHR。此外，我们已经研究了静脉注射后IEL迁移到淋巴组织中的能力，并将其与其体外运动能力进行了比较。

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期刊名称 Gut
作者
M E Baca; A M Mowat; S MacKenzie; D M Parrott;
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作者单位

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年(卷),期 1987(28),10
年度 1987
页码 1267–1274
总页数 8
原文格式 PDF
正文语种
中图分类肠道病毒与肝炎病毒;肝及胆疾病;肠疾病;
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1. Cytotoxic differentiation of mouse gut thymodependent and independent intraepithelial T lymphocytes is induced locally. Correlation between functional assays, presence of perforin and granzyme transcripts, and cytoplasmic granules. [J] . D Guy-Grand, M Malassis-Seris, C Briottet, The Journal of Experomental Medicine . 1991,第6期

机译：小鼠肠道胸腺依赖和独立的上皮内T淋巴细胞的细胞毒性分化是局部诱导的。功能测定，穿孔素和颗粒酶转录本的存在以及细胞质颗粒之间的相关性。
2. Virus-Induced Activation of Self-Specific TCRalphabeta CD8alphaalpha Intraepithelial Lymphocytes Does Not Abolish Their Self-Tolerance in the Intestine. [J] . Saurer L, Seibold I, Rihs S, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2004,第7期

机译：病毒诱导的自我特异性TCRalphabeta CD8alphaalpha上皮内淋巴细胞的激活不会消除其在肠道中的自我耐受性。
3. Capacity of genetically different T lymphocytes to induce lethal graft-versus-host disease correlates with their capacity to generate suppression but not with their capacity to generate anti-F1 killer cells. A non-H-2 locus determines the inability to induce lethal graft-versus-host disease. [J] . E H Van Elven, A G Rolink, F V Veen, The Journal of Experomental Medicine . 1981,第6期

机译：遗传上不同的T淋巴细胞诱导致命的移植物抗宿主病的能力与其产生抑制的能力有关，但与它们产生抗F1杀伤细胞的能力无关。非H-2基因座决定了无法诱导致命的移植物抗宿主病。
4. Functional characteristics of intraepithelial lymphocytes from mouse small intestine. II. In vivo and in vitro responses of intraepithelial lymphocytes to mitogenic and allogeneic stimuli. [O] . A M Mowat, S MacKenzie, M E Baca, 1986

机译：小鼠小肠上皮内淋巴细胞的功能特性。二。上皮内淋巴细胞对促有丝分裂和同种异体刺激的体内和体外反应。
5. Functional characteristics of intraepithelial lymphocytes from mouse small intestine. III. Inability of intraepithelial lymphocytes to induce a systemic graft-versus-host reaction is because of failure to migrate in vivo. [O] . Baca, M E, Mowat, A M, MacKenzie, S, 1987

机译：小鼠小肠上皮内淋巴细胞的功能特性。三，上皮内淋巴细胞不能诱导全身性移植物抗宿主反应是由于不能在体内迁移。
6. Characteristics of a Xenogeneic Lymphocyte Transfer Reaction: Its Use in the Study of Graft versus Host Capability of Mouse Lymphoid Cells from Various Anatomic Sites. [R] . Catanzaro, P. J., Graham, R. C., Powell, A. E., 1976

机译：异种淋巴细胞转移反应的特征：其用于研究来自不同解剖位点的小鼠淋巴细胞的移植物抗宿主能力。

Functional characteristics of intraepithelial lymphocytes from mouse small intestine. III. Inability of intraepithelial lymphocytes to induce a systemic graft-versus-host reaction is because of failure to migrate in vivo.

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